Protein Alignment Bx and LMX1A

DIOPT Version :9

• Sequence 1: NP_001259687.1
• Gene: Bx / 32846
• FlyBaseID: FBgn0265598
• Length: 424
• Species: Drosophila melanogaster
• Sequence 2: NP_001167540.1
• Gene: LMX1A / 4009
• HGNCID: 6653
• Length: 382
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 80/301 - (26%)
• Similarity: 118/301 - (39%)
• Gaps: 56/301 - (18%)

  Fly    91 LCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGY 155
            :|.||.:.|.||:|||..|..|||.|::|..|.   ..:.:|.:.:...:.||.||.:||...
Human    34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCK---EPLETTCFYRDKKLYCKYDYEKLFAVK-- 93

  Fly   156 CAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLVFASMA 220
            |..|.:.|...|.||||:.:||||.||.|..|..:...||.|.|.|.::||:.|||:.....|:.
Human    94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLV 158

  Fly   221 NHPMLKRHVSSLGQGSPTGA-AGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNNNNNGPQT 284
                           ||..: :|..:....|.....|.|        .|....|..:.....|:|
Human   159 ---------------SPAASDSGKSDDEESLCKSAHGAG--------KGTAEEGKDHKRPKRPRT 200

  Fly   285 --PTGGGSPFAAA-AAAAAAAAHMKNQLGASSXNKALGMGAAGAVVPGSGVGAGVGVGVGAASQQ 346
              .|.....|.|: ..::.....::..|.|.:                     |:.|.|   .|.
Human   201 ILTTQQRRAFKASFEVSSKPCRKVRETLAAET---------------------GLSVRV---VQV 241

  Fly   347 FYSGFGLQHQHQHQQHHQQQQQQQQLMGLGLGMGGGGGVGG 387
            ::.....:.:...::..||||.||....|......|||..|
Human   242 WFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAG 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	19/53 (36%)
		LIM2_dLMO	156..210	CDD:188776	23/53 (43%)
LMX1A	NP_001167540.1	LIM1_Lmx1a	35..86	CDD:188756	19/53 (36%)
		LIM2_Lmx1a_Lmx1b	94..148	CDD:188764	23/53 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..208		9/54 (17%)
		Homeobox	198..252	CDD:395001	11/77 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	252..285		11/31 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910