DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and LMO2

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_005565.2	Gene:	LMO2 / 4005	HGNCID:	6642	Length:	227	Species:	Homo sapiens

Alignment Length:	192	Identity:	80/192 - (41%)
Similarity:	93/192 - (48%)	Gaps:	38/192 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 SGGAGGGNNGNGNVQSIAAAANNNNNNNNNGSQ-------------------------------- 90
            |||.|||..|....:.:.|.|............
Human    28 SGGDGGGGGGARAPEGVRAPAAGQPRATKGAPPPPGTPPPSPMSSAIERKSLDPSEEPVDEVLQI 92

  Fly    91 -----LCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLF 150
                 .|.||.::|.|||.|:|:|..||||||.|..|.|||||||..||.|....||:|||||||
Human    93 PPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLF 157

  Fly   151 GNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYD-YE 211
            |..|.||:|.|.|.|:||.||.:..|||||||.|..|...||||||:.|..:.|:||.| ||
Human   158 GQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYE 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	31/53 (58%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	30/54 (56%)
LMO2	NP_005565.2	LIM1_LMO2	99..154	CDD:188770	32/54 (59%)
LMO2	NP_005565.2	LIM2_LMO2	163..218	CDD:188771	30/54 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45787
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010