DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and pdlim7

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_957134.1	Gene:	pdlim7 / 393813	ZFINID:	ZDB-GENE-040426-2092	Length:	419	Species:	Danio rerio

Alignment Length:	145	Identity:	48/145 - (33%)
Similarity:	74/145 - (51%)	Gaps:	12/145 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 NVQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDC-RLGEVGSTL 133
            |..||..||..:..:::..:.|||.|.|.|:.||:: ||...||.:  :..||.| ||.:.|...
Zfish   222 NRSSILQAAQQSPAHSSTATPLCAACSKIIRGRYVV-ALGRSWHPE--EFMCCQCKRLLDEGGFF 283

  Fly   134 YTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDR-F 197
            ..||:: .|.:.|...:...  ||.|.|:|..  .:|.|....||::||.|..|  :..:.:: |
Zfish   284 EEKGSI-YCSKCYDNRYSPN--CAKCKKIITG--EIMHALKMTYHVQCFLCAAC--KLPIRNQAF 341

  Fly   198 YLCENKILCEYDYEE 212
            |:.|.:..||.|||:
Zfish   342 YMEEGEPYCERDYEK 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	20/54 (37%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	18/54 (33%)
pdlim7	NP_957134.1	PDZ_signaling	3..81	CDD:238492
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..232		5/9 (56%)
		LIM1_Enigma	244..295	CDD:188836	20/54 (37%)
		LIM2_Enigma	303..354	CDD:188840	18/54 (33%)
		LIM3_Enigma	362..416	CDD:188842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910