DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and pdlim5b

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_956490.1	Gene:	pdlim5b / 393165	ZFINID:	ZDB-GENE-040426-908	Length:	628	Species:	Danio rerio

Alignment Length:	311	Identity:	60/311 - (19%)
Similarity:	101/311 - (32%)	Gaps:	116/311 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 QQQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGGAGGGNNGNGNVQSIAAAANNNNNNNNNG 88
            :..|:|:|..|.|...::..|:.:.:.:|..:..| .||....|||    |:||...:...:::.
Zfish   330 ENDQAQESRPGKNEAVEDLQPSSHSSSSVFTMSKS-PAGATRQGNG----ISAAPAKHWQTSSSS 389

  Fly    89 S-----------------------------------------------------------QLCAG 94
            |                                                           .:||.
Zfish   390 SAGFPRSGGAGVAPTGPSVGRGVSSSVPKGPERPVPQPHPRDQDESVVQRAEHMPAGTRTPMCAH 454

  Fly    95 CGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNL--MLCKRDYLRLFGNTGYCA 157
            |...|:..:|: |:...||:|...|..|...|.:|| .:..:|::  :||..::|     ...|.
Zfish   455 CNTVIRGPFLV-AMGKSWHKDEFTCSHCRSSLADVG-FVEERGSVYCVLCYEEFL-----APTCF 512

  Fly   158 ACSKVIPAFEMVMRARTNVYHLECFACQQC-----NHRFCVGDRFYLCENKIL---------CEY 208
            .|.|.|  ...|:.|....:|:.||.|..|     |:.|.:.||...||....         |::
Zfish   513 QCHKKI--IGEVINALKQTWHVNCFLCASCKQPIGNNTFHLEDRQPYCEKDYYSLFGTGCHGCDF 575

  Fly   209 DYE---------------------------ERLVFASMANHPMLKRHVSSL 232
            ..|                           |...|.|..:.|:.|:|..::
Zfish   576 PIEAGDKFLEALGFTWHDTCFVCAVCSTSLEGQTFFSKKDKPLCKKHAHTV 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	17/55 (31%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	18/67 (27%)
pdlim5b	NP_956490.1	PDZ_signaling	11..80	CDD:238492
		DUF4749	243..335	CDD:292558	1/4 (25%)
		LIM1_Enigma_like	452..503	CDD:188747	16/52 (31%)
		LIM2_Enigma_like	511..562	CDD:188748	17/52 (33%)
		LIM	570..624	CDD:295319	8/53 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910