DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and Lims2

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_006254658.1	Gene:	Lims2 / 361303	RGDID:	1305273	Length:	341	Species:	Rattus norvegicus

Alignment Length:	160	Identity:	44/160 - (27%)
Similarity:	70/160 - (43%)	Gaps:	24/160 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGN 152
            |..:|..|.:.|:.| ::.||...||.:...|..|:...  :|...|.|..|..|:..|.:|||:
  Rat   194 GIPICGACRRPIEGR-VVNALGKQWHVEHFVCAKCEKPF--LGHRHYEKKGLAYCETHYNQLFGD 255

  Fly   153 TGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLVFA 217
            .  |..||.||..  .|:.|.:..:.:.||:|..||.:..:.::|...:.|.:|:..||
  Rat   256 V--CYNCSHVIEG--DVVSALSKAWCVNCFSCSACNMKLTLKNKFVEFDMKPVCKRCYE------ 310

  Fly   218 SMANHPM-LKRHVSSL-------GQGSPTG 239
               ..|: ||:.:..|       .|..|.|
  Rat   311 ---RFPLELKKRLKKLSDLSSRKAQPKPVG 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	15/53 (28%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	15/53 (28%)
Lims2	XP_006254658.1	LIM1_PINCH	15..73	CDD:188717
		LIM2_PINCH	76..127	CDD:188718
		LIM3_PINCH	140..190	CDD:188719
		LIM4_PINCH	196..249	CDD:188720	15/55 (27%)
		LIM5_PINCH	257..310	CDD:188721	15/54 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010