DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and Lpxn

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_038964643.1	Gene:	Lpxn / 293783	RGDID:	1304981	Length:	398	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	43/148 - (29%)
Similarity:	65/148 - (43%)	Gaps:	13/148 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEV--GSTLYTKGNLMLCKRDYLRLFG 151
            |..||.|...|.|: :|.|::..||.:...|..|    |||  ....:.|.....|::|:|.:|
  Rat   220 SPRCAYCAAPITDK-VLTAMNKTWHPEHFFCSHC----GEVFGAEGFHEKDKKPYCRKDFLAMF- 278

  Fly   152 NTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERL-V 215
             :..|..|::  |..|..:.|...|:|.|||.|..|...|..|. |:..:.:..||..|..|. .
  Rat   279 -SPKCGGCNR--PVLENYLSAMNTVWHPECFVCGDCFSSFSSGS-FFELDGRPFCELHYHHRRGT 339

  Fly   216 FASMANHPMLKRHVSSLG 233
            .......|:..|.:|::|
  Rat   340 LCHDCGQPITGRCISAMG 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	16/55 (29%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	17/53 (32%)
Lpxn	XP_038964643.1	LIM1_Leupaxin	162..216	CDD:188790
		LIM	223..274	CDD:413332	16/55 (29%)
		LIM	282..334	CDD:413332	17/54 (31%)
		LIM4_Paxillin_like	341..392	CDD:188725	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010