DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and LHX6

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011516823.1	Gene:	LHX6 / 26468	HGNCID:	21735	Length:	407	Species:	Homo sapiens

Alignment Length:	163	Identity:	60/163 - (36%)
Similarity:	79/163 - (48%)	Gaps:	7/163 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGN 152
            |..:|:.||..|.|||||:..:::||..||:|..|...|.:..| .|.|...:.||.||...||.
Human    95 GKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNS-CYIKNKEIFCKMDYFSRFGT 158

  Fly   153 TGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERLV-- 215
            .  ||.|.:.|.|.:.|.|||.|.|||.||||..|..:...|:.|.|.|.|:||...|:..:.
Human   159 K--CARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYDTMIENL 221

  Fly   216 --FASMANHPMLKRHVSSLGQGSPTGAAGAQNT 246
              .|...|...|:..|.|.....|..|..|:.:
Human   222 KRAAENGNGLTLEGAVPSEQDSQPKPAKRARTS 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	21/53 (40%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	25/53 (47%)
LHX6	XP_011516823.1	LIM1_Lhx6	99..152	CDD:188766	21/53 (40%)
		LIM2_Lhx6	160..214	CDD:188768	25/53 (47%)
		Homeobox	252..304	CDD:278475	0/3 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910