DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and ABLIM3

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001287944.1	Gene:	ABLIM3 / 22885	HGNCID:	29132	Length:	683	Species:	Homo sapiens

Alignment Length:	162	Identity:	47/162 - (29%)
Similarity:	66/162 - (40%)	Gaps:	20/162 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 GSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRL-GEVGSTLYTKGNLMLCKRDYLRLFG 151
            |...||||.:.|:....|.|||..||..|.||..|...| ||    ..:|..:..|:.||...||
Human   147 GPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQTCSVILTGE----YISKDGVPYCESDYHAQFG 207

  Fly   152 NTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKI---LCEYDYEER 213
            ..  |..|.:.|..  .|:.|....||..|..|.:|:..|..|:..||..:::   :|:.
Human   208 IK--CETCDRYISG--RVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQ----- 263

  Fly   214 LVFASMANHPMLKRHVSSLGQGSPTGAAGAQN 245
               |:.|...:..|..|......|..:.|:.|
Human   264 ---AARAEKKLKHRRTSETSISPPGSSIGSPN 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	20/54 (37%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	15/56 (27%)
ABLIM3	NP_001287944.1	LIM1_abLIM	23..74	CDD:188713
		LIM2_abLIM	79..134	CDD:188714
		LIM3_abLIM	151..202	CDD:188715	20/54 (37%)
		LIM4_abLIM	210..265	CDD:188716	15/64 (23%)
		AbLIM_anchor	274..647	CDD:292800	5/19 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	372..472
		VHP	648..683	CDD:128458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910