DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_036008777.1	Gene:	Tgfb1i1 / 21804	MGIID:	102784	Length:	496	Species:	Mus musculus

Alignment Length:	147	Identity:	42/147 - (28%)
Similarity:	70/147 - (47%)	Gaps:	9/147 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNT 153
            |..|..|.:.|:.: ::.||...||.:...|..|....||.|  .:.:.....|:||:|:||...
Mouse   319 SPRCGFCNQPIRHK-MVTALGTHWHPEHFCCVSCGEPFGEEG--FHEREGRPYCRRDFLQLFAPR 380

  Fly   154 GYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCE-YDYEERLVFA 217
              |..|..  |..:..:.|.:.::|.:||.|::|...|. |..|:..|.:.||| :.:.:|....
Mouse   381 --CQGCQG--PILDNYISALSALWHPDCFVCRECLAPFS-GGSFFEHEGRPLCENHFHAQRGSLC 440

  Fly   218 SMANHPMLKRHVSSLGQ 234
            :....|:..|.||:||:
Mouse   441 ATCGLPVTGRCVSALGR 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	14/53 (26%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	16/54 (30%)
Tgfb1i1	XP_036008777.1	Paxillin	4..>128	CDD:397550
		LIM1_Paxillin_like	263..315	CDD:259830
		LIM2_Paxillin_like	322..373	CDD:188723	14/53 (26%)
		LIM	381..433	CDD:413332	16/54 (30%)
		LIM4_Leupaxin	440..491	CDD:188796	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920