DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and alp-1

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001023371.1	Gene:	alp-1 / 177701	WormBaseID:	WBGene00001132	Length:	1424	Species:	Caenorhabditis elegans

Alignment Length:	247	Identity:	56/247 - (22%)
Similarity:	85/247 - (34%)	Gaps:	50/247 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 MDITKTEPGLVGLSSNQQQQQ--------QQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGG 60
            :|..|...|..|.|.:..||.        ::.:.::....|:|....| :..|.|::.....:..
Worm  1180 IDENKKAGGSNGSSQHHNQQGSSYTKTSFERTTTETRPQQNTGAPRAG-DFRGTGHLTTTTTTQQ 1243

  Fly    61 AGGG-----------------NNGNGNVQSIAAAANNNNNN--------NNNGSQLCAGC-GKHI 99
            .||.                 ..|..........||::...        ..:|.:.|..| .:||
Worm  1244 NGGRAPFCESCKQQIRGAFVLATGKSWCPEHFVCANSSCRRRLLECGFVEEDGQKFCESCFEQHI 1308

  Fly   100 QDRY----------LLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTG 154
            ..|.          .|.||...||..|..|..|....|  .|..|.:..|..|::|:..||  |.
Worm  1309 APRCNKCSKPIISDCLNALQKKWHPTCFTCAHCQKPFG--NSAFYLEQGLPYCEQDWNALF--TT 1369

  Fly   155 YCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILC 206
            .|.:|...|.|.:..:.|..|.:|..||.|.:|||.. .|:.|:....:..|
Worm  1370 KCVSCRYPIEAGDRWVEALGNAFHSNCFTCARCNHNL-EGESFFAKNGQPFC 1420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	18/64 (28%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	16/51 (31%)
alp-1	NP_001023371.1	PDZ_signaling	5..80	CDD:238492
		DUF4749	137..>197	CDD:292558
		ZM	137..162	CDD:128974
		LIM_ALP_like	220..271	CDD:188746
		LIM1_Enigma_like_1	1251..1304	CDD:188839	5/52 (10%)
		LIM	1312..1363	CDD:295319	13/52 (25%)
		LIM3_Enigma_like_1	1371..1424	CDD:188845	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920