DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and pxl-1

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001021185.2	Gene:	pxl-1 / 175831	WormBaseID:	WBGene00016197	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	53/232 - (22%)
Similarity:	97/232 - (41%)	Gaps:	33/232 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ITKTEPGLVGLSSNQQQQQQQQSQQSNAGMNSGGQNNGPNPNGNGNVVNVVNSGGAGGGNNGNGN 70
            :::.|...:..||:::........||.:.:.|.|::...:|..:.:::..:           ||.
Worm   108 LSQVEEPPIRASSSRKSLGPPSQAQSYSDVRSNGRSPSRDPLHSDSMIGTM-----------NGE 161

  Fly    71 VQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYT 135
            :.|     .:..|....|.  ||.|||.|..:.:: ||..:||.:...|..|...||:  ...:.
Worm   162 LSS-----KHGVNTIPKGD--CAACGKPIIGQVVI-ALGKMWHPEHYTCCECGAELGQ--RPFFE 216

  Fly   136 KGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVG-DRFYL 199
            :.....|:.||...|  :..|..|.:.|.  :..:......:|:|||.|.:||..|  | |.|:.
Worm   217 RNGRAFCEEDYHNQF--SPKCQGCHRAIT--DRCVSVMNKNFHIECFTCAECNQPF--GEDGFHE 275

  Fly   200 CENKILCEYDYEERLVFASMAN---HPMLKRHVSSLG 233
            ...:..|:.|:..  :||...|   .|:....:::||
Worm   276 KNGQTYCKRDFFR--LFAPKCNGCSQPITSNFITALG 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	15/53 (28%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	15/54 (28%)
pxl-1	NP_001021185.2	LIM1_Leupaxin	174..228	CDD:188790	17/58 (29%)
		LIM	235..290	CDD:278823	16/60 (27%)
		LIM3_Paxillin_like	294..346	CDD:188724	4/17 (24%)
		LIM4_Paxillin_like	353..404	CDD:188725
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920