DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and Lhx3

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_038962056.1	Gene:	Lhx3 / 170671	RGDID:	71078	Length:	416	Species:	Rattus norvegicus

Alignment Length:	318	Identity:	87/318 - (27%)
Similarity:	125/318 - (39%)	Gaps:	74/318 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGY 155
            :||||.:||.||::|:|||..||..||||..|...|.|   ..:::|..:.||.|:.:.||..
  Rat    20 MCAGCDQHILDRFILKALDRHWHSKCLKCSDCHVPLAE---RCFSRGESVYCKDDFFKRFGTK-- 79

  Fly   156 CAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCE-NKILCEYDYE-----ERL 214
            ||||...||..::|.||:..||||.||||..|..:...||.|||.| ::::|:.|||     |..
  Rat    80 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYETAKQREAE 144

  Fly   215 VFASMANHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGPGGGNVNGVGMVNGPRTPGDHNNNN 279
            ..|......:..:.:.:|.....|....|::....|  ....|.::..|.:....|.|..
  Rat   145 ATAKRPRTTITAKQLETLKSAYNTSPKPARHVREQL--SSETGLDMRVVQVSARSRPPAP----- 202

  Fly   280 NGPQTPTGGGSPF----------------------AAAAAAAAAAAHMKNQLGASSXNK------ 316
            .|.:.|...|.|.                      |..........:||...|:|. :|
  Rat   203 EGARAPREAGQPLTIPTPQVWFQNRRAKEKRLKKDAGRQRWGQYFRNMKRSRGSSKSDKDSIQEG 267

  Fly   317 --------------ALGMGAAGAVV-----PGSGVGAGVGVGVGAASQQFYSGFGLQH 355
                          ...||.|..:.     |...:|..|| |:|:        |.|:|
  Rat   268 QDSDAEVSFTDEPSMADMGTANGLYSSLGEPAPALGRPVG-GLGS--------FTLEH 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	24/53 (45%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	25/54 (46%)
Lhx3	XP_038962056.1	LIM1_Lhx3b	18..72	CDD:188851	24/54 (44%)
		LIM2_Lhx3_Lhx4	80..135	CDD:188762	25/54 (46%)
		Homeobox	150..233	CDD:395001	12/89 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910