DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and AgaP_AGAP011134

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_309513.3	Gene:	AgaP_AGAP011134 / 1270792	VectorBaseID:	AGAP011134	Length:	501	Species:	Anopheles gambiae

Alignment Length:	497	Identity:	118/497 - (23%)
Similarity:	166/497 - (33%)	Gaps:	185/497 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SIAAAANNNNNNNNNG------SQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGS 131
            :..:...:|.:|...|      ...||||.|.|.|::||..|:..||..|::  ||:|. ..:..
Mosquito     2 AFGSVLQHNQHNIGRGEPPSGLGDPCAGCNKPILDKFLLNVLERGWHATCVR--CCECH-QPLAD 63

  Fly   132 TLYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDR 196
            ..:::.:.:.|:.|:.|.:|..  |:.|.:.|...::|.:.|..|:||.||.|..|..:...|::
Mosquito    64 KCFSRESKLYCRNDFFRRYGTK--CSGCGQGIAPSDLVRKPRDKVFHLNCFTCCICRKQISTGEQ 126

  Fly   197 FY-LCENKILCEYDYEERLVFASMANHPMLKRHVSSLGQ--------------GSPTGAAGAQNT 246
            .| |.:||.:|:.||     ......|||....:.|..:              |..:|.|||
Mosquito   127 LYVLDDNKFICKDDY-----ILGKGPHPMTDSLMGSASEDEDEEDQMRPGVLAGLVSGGAGA--- 183

  Fly   247 AGGLLGGGPGGGNVNGV----------------GMVNG-PRTPGDHNNNNNGPQTPTGGGSPFAA 294
            ||...|.||.|.:...|                |.::| |...||....|..|.  .|.||....
Mosquito   184 AGLHHGDGPLGASDLSVQSMSTDSKTGHDDSDQGSLDGDPDCRGDSQAENKSPD--DGAGSKRRG 246

  Fly   295 AAAAAAA----------------AAHMKNQLGASS-----------XNK-----------ALGMG 321
            ......|                ..|::.||...:           .||           ::|.|
Mosquito   247 PRTTIKAKQLEVLKNAFSQTPKPTRHIREQLAKETGLPMRVIQVWFQNKRSKERRLKQLTSMGRG 311

  Fly   322 A--AGA---------VVPGSGVGAGV---GVGVGAASQQFYSGFGLQHQHQHQ------------ 360
            .  .||         :.||     |:   |....||..:|..|:|....|.|.
Mosquito   312 PFFGGARKMRGFPMNLSPG-----GLDEPGFPYFAADGKFDFGYGGPPFHPHDAPFFGGHPGAGP 371

  Fly   361 ---------QHH-----------------------------------------------QQQQQQ 369
                     ..|                                               ||....
Mosquito   372 MPFGGPGGPMDHPIPMVGDFGMAGPDGGPGGMLGGPGGPGGPGGGPGGFMGGPGGPGGPQQGHGP 436

  Fly   370 QQLMGLGLGMGGGGGVGGGGAGSAGG------PGGGAGGGGG 405
            ..:||.|:| |||||.||||.|..||      ||||.|||||
Mosquito   437 DGMMGGGVG-GGGGGGGGGGGGGGGGPHAPSRPGGGGGGGGG 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	17/53 (32%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	18/54 (33%)
AgaP_AGAP011134	XP_309513.3	LIM1_Lhx1_Lhx5	27..78	CDD:188753	17/53 (32%)
		LIM2_Lhx1_Lhx5	86..141	CDD:188761	18/54 (33%)
		Homeobox	247..300	CDD:278475	6/52 (12%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910