DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and WTIP

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_011524754.1	Gene:	WTIP / 126374	HGNCID:	20964	Length:	472	Species:	Homo sapiens

Alignment Length:	136	Identity:	45/136 - (33%)
Similarity:	62/136 - (45%)	Gaps:	21/136 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LCAGCGKHIQD-RYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTG 154
            :|..||..|.. :...:|:..|:|.||..|..|..||.  |...|..|..:.|:.|:|    .:|
Human   224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLR--GKAFYNVGEKVYCQEDFL----YSG 282

  Fly   155 Y------CAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCV-GDRFYL-CENKILCEYDYE 211
            :      |:.|..:|  .||:::|....||..||.|..||.  |: |..|.: .||.|.|..||
Human   283 FQQTADKCSVCGHLI--MEMILQALGKSYHPGCFRCSVCNE--CLDGVPFTVDVENNIYCVRDY- 342

  Fly   212 ERLVFA 217
             ..|||
Human   343 -HTVFA 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	17/54 (31%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	20/55 (36%)
WTIP	XP_011524754.1	LIM1_Ajuba_like	225..278	CDD:188738	17/54 (31%)
		LIM2_Ajuba_like	290..342	CDD:188741	20/55 (36%)
		LIM	350..404	CDD:295319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910