DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and lhx6

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_002941184.1	Gene:	lhx6 / 100493242	XenbaseID:	XB-GENE-493341	Length:	389	Species:	Xenopus tropicalis

Alignment Length:	178	Identity:	61/178 - (34%)
Similarity:	89/178 - (50%)	Gaps:	7/178 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKG 137
            |:.:..:::::..::|..:|:.||..|.|||||:..:::||..||:|..|...|.:..| .|.|.
Frog    77 SVCSPPSSSSSVPSDGKNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQHNS-CYIKN 140

  Fly   138 NLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCEN 202
            ..:.||.||...||..  ||.|.:.|.|.:.|.|||.|.|||.||||..|..:...|:.|.|.|.
Frog   141 KEIFCKMDYFSRFGTK--CARCGRQIYASDWVRRARGNAYHLACFACYSCKRQLSTGEEFGLVEE 203

  Fly   203 KILCEYDYEERLV----FASMANHPMLKRHVSSLGQGSPTGAAGAQNT 246
            |:||...|:..:.    .|...|...|:..|.|.....|..|..|:.:
Frog   204 KVLCRIHYDTMIENLKRAAENGNGITLEGAVPSEQDSQPKPAKRARTS 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	21/53 (40%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	25/53 (47%)
lhx6	XP_002941184.1	LIM1_Lhx6	96..149	CDD:188766	21/53 (40%)
		LIM2_Lhx6	157..211	CDD:188768	25/53 (47%)
		Homeobox	249..302	CDD:365835	0/3 (0%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910