DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bx and arx

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_002933659.1	Gene:	arx / 100486727	XenbaseID:	XB-GENE-483940	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	358	Identity:	79/358 - (22%)
Similarity:	96/358 - (26%)	Gaps:	171/358 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 SSN-------QQQQQQQQSQQSNAGMNSGGQNNGPNPNGNGNVVN-------VVNSGGAGGGNNG 67
            |||       :||..|.|||||        |...| |.|.|....       :::|..|    :|
Frog   226 SSNPNRAHLQEQQHPQFQSQQS--------QQQQP-PPGCGTDAELSPKEELMLHSSDA----DG 277

  Fly    68 NGNVQSIAAAANNNNNNNNNGSQLCAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGST 132
            .....|:..:|         ||....|..|..|.||                           .|
Frog   278 KDGEDSVCLSA---------GSDSEEGMLKRKQRRY---------------------------RT 306

  Fly   133 LYTKGNLMLCKRDYLRLFGNTGYCAACSKVIPAFEMVMR-----ARTNVYHLECFACQQCNHRFC 192
            .:|...|    .:..|.|..|.|    ..|....|:.||     ||..|:    |..::...|
Frog   307 TFTSYQL----EELERAFQKTHY----PDVFTREELAMRLDLTEARVQVW----FQNRRAKWR-- 357

  Fly   193 VGDRFYLCENKILCEYDYEERLVFASMANHPMLKRHVSSLGQGSPTGAAGAQNTAGGLLGGGPGG 257
                                             ||.           .||||..|.||...||
Frog   358 ---------------------------------KRE-----------KAGAQTHAPGLPFPGP-- 376

  Fly   258 GNVNGVGMVNGPRTPGDHNNNNNGPQTPTGGGSPF------------AAAAAAAAAAAHMKNQLG 310
                         ....|      |..|....|||            |||||||||...:.....
Frog   377 -------------LSASH------PLGPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPH 422

  Fly   311 ASSXNKALGMGAAGAVVPGSGVGAGVGVGVGAA 343
            .|            |.:|.||...|:...:|||
Frog   423 GS------------AALPPSGSPLGLSTFLGAA 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	8/53 (15%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	9/58 (16%)
arx	XP_002933659.1	Homeobox	305..358	CDD:365835	16/99 (16%)
arx	XP_002933659.1	OAR	500..518	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910