DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and isl2

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_001159513.1	Gene:	isl2 / 100306962	XenbaseID:	XB-GENE-487556	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	150	Identity:	54/150 - (36%)
Similarity:	78/150 - (52%)	Gaps:	6/150 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 AAANNNNNNNNNGSQLCAGCGKHIQDRYLLR-ALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNL 139
            :||...:.....|..:|.|||.||.|:|:|| :.|:.||..||||..|...|.| ..|.:.:...
Frog    11 SAAMGEHPKKKAGLAVCVGCGSHILDQYILRVSPDLEWHAACLKCAECSQYLDE-NCTCFVRDGK 74

  Fly   140 MLCKRDYLRLFGNTGYCAACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKI 204
            ..|||||:|||  :..|..|...:|..|:|||....|||.:||.|..|:.|...|:...|.:..:
Frog    75 TYCKRDYIRLF--SARCPRCQGTLPRSELVMRVGERVYHTDCFRCSVCSRRLLPGEEISLRDQDL 137

  Fly   205 LC--EYDYEERLVFASMANH 222
            ||  |::..:....:|:.:|
Frog   138 LCGAEHNLSDSGRPSSLRSH 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	24/54 (44%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	20/55 (36%)
isl2	NP_001159513.1	LIM1_Isl	27..81	CDD:188752	24/54 (44%)
		LIM2_Isl	89..143	CDD:188760	19/53 (36%)
		HOX	165..221	CDD:197696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910