DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bx and tgfb1i1

DIOPT Version :9

Sequence 1:	NP_001259687.1	Gene:	Bx / 32846	FlyBaseID:	FBgn0265598	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	XP_012825390.2	Gene:	tgfb1i1 / 100038241	XenbaseID:	XB-GENE-493249	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	144	Identity:	45/144 - (31%)
Similarity:	64/144 - (44%)	Gaps:	9/144 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    92 CAGCGKHIQDRYLLRALDMLWHEDCLKCGCCDCRLGEVGSTLYTKGNLMLCKRDYLRLFGNTGYC 156
            ||.|...|... ::.||...||.:...|..|...:||.|  .:.|.....|..||.||||  ..|
Frog   329 CALCELPIVQN-MVTALGCTWHPEHFCCKVCKKPIGEEG--FHEKDGEQYCSDDYFRLFG--AVC 388

  Fly   157 AACSKVIPAFEMVMRARTNVYHLECFACQQCNHRFCVGDRFYLCENKILCEYDYEERL-VFASMA 220
            |.||:.:.  |..:.|...::|.:||.|..|:..|..|. |:..|...|||..|..|. ...:..
Frog   389 AGCSEAVK--ESYISALGGLWHPQCFVCHVCHTPFINGS-FFEHEGLPLCETHYHSRRGSLCAGC 450

  Fly   221 NHPMLKRHVSSLGQ 234
            ..|:..|.|:::|:
Frog   451 EQPITGRCVTAMGK 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bx	NP_001259687.1	LIM1_LMO1_LMO3	92..146	CDD:188774	15/53 (28%)
Bx	NP_001259687.1	LIM2_dLMO	156..210	CDD:188776	18/53 (34%)
tgfb1i1	XP_012825390.2	Paxillin	<61..>117	CDD:397550
		LIM1_Paxillin_like	270..322	CDD:259830
		LIM2_Paxillin_like	329..380	CDD:188723	15/53 (28%)
		LIM3_Paxillin_like	388..440	CDD:188724	18/54 (33%)
		LIM4_Paxillin_like	447..498	CDD:188725	4/18 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010