DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and RNF17

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_011533454.1	Gene:	RNF17 / 56163	HGNCID:	10060	Length:	1699	Species:	Homo sapiens

Alignment Length:	149	Identity:	28/149 - (18%)
Similarity:	53/149 - (35%)	Gaps:	45/149 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 WSKSVMKRGTGDFRVWDIVLAPYQGRYHRAKIVDIFRCRYRVYFLDFGITEYTSKKNL------- 351
            |.|.......|...:|           :|.|::::.....||.:||.|.||...:.:|
Human  1305 WKKGEACAVRGSDTLW-----------YRGKVMEVVGGAVRVQYLDHGFTEKIPQCHLYPILLYP 1358

  Fly   352 ---TFCYELEKAQHNLAFRFEILGTRRQCPIPYINILEGIKHLEHTVLRSDINVRIHNILKDGGY 413
               .||...:  .||..            |:..:...:.|:.|:..:.:..:::          :
Human  1359 DIPQFCIPCQ--LHNTT------------PVGNVWQPDAIEVLQQLLSKRQVDI----------H 1399

  Fly   414 VIRLMKHIHECHMIHLFDD 432
            ::.|.|:..|...|||:.|
Human  1400 IMELPKNPWEKLSIHLYFD 1418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	9/40 (23%)
RNF17	XP_011533454.1	TUDOR	446..>553	CDD:278965
		TUDOR	702..870	CDD:278965
		TUDOR	758..852	CDD:119391
		TUDOR	990..1106	CDD:278965
		TUDOR	1043..1089	CDD:119391
		TUDOR	1253..1371	CDD:278965	16/78 (21%)
		TUDOR	1308..1353	CDD:119391	12/55 (22%)
		TUDOR	1486..1626	CDD:278965
		TUDOR	1560..1607	CDD:119391
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900