DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and rnf17

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_021334643.1	Gene:	rnf17 / 334519	ZFINID:	ZDB-GENE-030131-6451	Length:	1521	Species:	Danio rerio

Alignment Length:	407	Identity:	76/407 - (18%)
Similarity:	132/407 - (32%)	Gaps:	136/407 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 QPIRAVPKCVNSKEILSSLARNPRKSRLYPPHGGHMRSVVGTFY-----------KITDQIGEIA 73
            :|....||.|  :.::::...||          ||       ||           |:|.:|.|..
Zfish   382 KPTNPQPKLV--QYVVTTHIVNP----------GH-------FYVRYMAEHKLGQKLTKKISEFC 427

  Fly    74 IGTK---------LTGTVLLESLPVFYVTINGPGSKLLKCLAMGQVQLQELEQLPDYGEIFAFYD 129
            .|.:         .||::|..|           ....:.|    :|::.||.|    .|.|....
Zfish   428 SGERSFFTFSDEITTGSLLFIS-----------WKDDMWC----RVKVTELFQ----KECFQSVT 473

  Fly   130 KA-ENRISRIAINAPVHPMGYCAYMIDAAKYT--------NMSGMERIFALPD-----DLKKLPA 180
            |. .:.:||:           |.|.:|...:.        .:||:......||     ::.....
Zfish   474 KCLASEVSRL-----------CVYFLDYGFFKGFSIPSDGGLSGLNECLRRPDGITLIEMANWAP 527

  Fly   181 LTIKCRLVNV---------------AQMHIFITQNVRLRVLGSNGLELLVALIRNRTNIRKIPSA 230
            |.|||.|.::               ...::...:...::|.|.:|..|||       :::|...|
Zfish   528 LAIKCSLKDIIPADLVKGWSSEASEEMRNVLRNETAEMQVFGEDGDALLV-------DLKKTSMA 585

  Fly   231 QLPPISGDEYGNMDANDREVAKSFARYRPKRRERGSI-----------VRVHVTRIVSH----AE 280
            .|...|     .:...:..|....||:.......||.           :.|.|..:|||    ::
Zfish   586 DLKKNS-----MVSLREHLVFMELARFYCPVITTGSAPLLFYPSVQPSLNVEVNAMVSHVNTPSD 645

  Fly   281 FYARFADGPTVPTWSKSV-----MKRGTGDFRVW-----DIVLAPYQGRYHRAKIVDIFRCR-YR 334
            ||.:..:....|.....:     ..:...:.:|:     ...:|.:...:.|.::......| ..
Zfish   646 FYVQLVENTEYPLLHSKLQDCYNQPKSNNECQVYCPSLSQACVAFHDQEWSRVQVTGFPGGRMVE 710

  Fly   335 VYFLDFGITEYTSKKNL 351
            |.|:|||.....|.|:|
Zfish   711 VRFVDFGYKRTLSVKDL 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	10/41 (24%)
rnf17	XP_021334643.1	RING_Ubox	8..60	CDD:327409
		TUDOR	394..534	CDD:306940	36/186 (19%)
		TUDOR	633..746	CDD:306940	19/95 (20%)
		TUDOR	865..977	CDD:306940
		TUDOR	1092..1214	CDD:306940
		TUDOR	1326..1450	CDD:306940
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900