DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and Tdrd1

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_038959137.1	Gene:	Tdrd1 / 292129	RGDID:	1306140	Length:	1174	Species:	Rattus norvegicus

Alignment Length:	400	Identity:	81/400 - (20%)
Similarity:	142/400 - (35%)	Gaps:	137/400 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 KLTGTVLLESLP-VFYVTINGPGSKLLKCLAMGQVQLQEL--------EQLPDYGEI-FAFY--D 129
            ::.|||.....| .|||.:.  .|::|:.:......|:|.        ..||..||: .|.|  |
  Rat   259 EIKGTVTEFKHPGHFYVQLY--SSEVLEYMNQLSASLKETYANMVPEDGYLPVKGEVCVAKYTVD 321

  Fly   130 KAENRISRIAINAPVHPMGYCAYM--IDAAKYTN--MSGMERIFALPDDLKKLPALTIKCRLVN- 189
            :..||    |:...|..:...|::  ||   |.|  :..::||..|...:...|...|||.:..
  Rat   322 QTWNR----AVVEGVDVLQKKAHVLYID---YGNEEIIPVDRIHQLSRSISLFPPSAIKCYVSGV 379

  Fly   190 ------------VAQMHIFITQNVRLR----------------VLGSNGLELLVALIRNRTNIR- 225
                        ||...:...|...::                ||.|:|.:|...|:.....::
  Rat   380 VPAAGEWTEDCVVAVKALLFEQYCSIKVVDISEEEGLTCAVDVVLQSSGKQLDHVLVEMGYGVKP 444

  Fly   226 KIPSAQ---LPPISGDEYGNMDANDREVAKSFARYRPKRRERGSIVRVHVT--------RIVSHA 279
            ..||::   :.|.:.::.|.:.|.:|..|           ||.::|...:|        .:|:|.
  Rat   445 DEPSSKKQSMDPGTSEDTGRLTAENRIGA-----------ERNALVPTVLTLNVGDEFCGVVAHI 498

  Fly   280 E-----FYARFADGPTVPTWSKSVMK-----RGTGDF--RVWDIVLAPY--QGRYHRAKIVDIFR 330
            :     |..:...|..:....:|:.:     ....||  .:.|:..|.:  ..:::||.::
  Rat   499 QTPEDFFCQQLQSGHKLAELQESLSEYCSHVTPRSDFYPTIGDMCCAQFSEDDQWYRASVL---- 559

  Fly   331 CRYR------VYFLDFGITEYTSKKNLTFCYELEKAQHNLAFRFEILGTRRQCPI---------P 380
             .|.      |.::|:|                         .||||..:|.|||         .
  Rat   560 -AYASEESVLVGYVDYG-------------------------NFEILSLKRLCPIIPKLLDLPMQ 598

  Fly   381 YIN-ILEGIK 389
            .:| :|.|:|
  Rat   599 ALNCVLAGVK 608

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	8/48 (17%)
Tdrd1	XP_038959137.1	zf-MYND	162..198	CDD:396356
		Tudor_TDRD1_rpt1	262..391	CDD:410479	34/137 (25%)
		Tudor_TDRD1_rpt2	512..593	CDD:410480	20/110 (18%)
		TUDOR	709..825	CDD:395449
		Tudor_SF	938..1053	CDD:413384
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000