DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and Tdrd5

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_006250099.1	Gene:	Tdrd5 / 289129	RGDID:	1307078	Length:	1046	Species:	Rattus norvegicus

Alignment Length:	493	Identity:	108/493 - (21%)
Similarity:	175/493 - (35%)	Gaps:	137/493 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 FNLMKTE-SIPSCLLQPIRAVPKCVNSKEILSSLARNPRKSRLYPPHGGHMRSVVGTFYKITDQI 69
            |.:.||. |.|...::|    ||.|.|.|.: .:......|||  .|...:..:..||..:..||
  Rat   228 FPVTKTRFSQPISNMEP----PKQVLSMEKI-PMFNTVEASRL--SHTEKLNQLESTFKSVIAQI 285

  Fly    70 GEIAIGTKLTGTV--LLESLPVFYVTINGPG---SKLLKCLAMGQVQLQELEQLPDYGEIFAFYD 129
            |.       .|||  .|:....|.|:....|   ||||     |:.:|...|||..  :...|.:
  Rat   286 GP-------GGTVDPDLKHKIKFVVSKFPQGLFISKLL-----GEFELVFKEQLSP--KQLGFLN 336

  Fly   130 KAE-----NRISRIAIN-------------APVHPMG-------YCAYMIDAAKYTNMSGMERIF 169
            ..|     :.|.|:..:             .|:.|.|       .|....|.....|      .:
  Rat   337 VTELVGALSDILRVEFSEEKQDLLVFDADLRPLLPAGPLSSVRNSCLVQPDKRIEAN------AW 395

  Fly   170 ALPDDLKKLPALTIK-----CRLVN--VAQMHIFITQNVRLRVLGSNGLELLVALIRNRTNIRKI 227
            |.......|..:.:|     |.|.|  .|:...:...|:.::     .|:|.|...:::.:: .:
  Rat   396 ASSPSRNSLSTVAVKKTTWDCPLKNHKEAEQKAYKKPNLVVK-----PLQLQVETNKSQLSL-SM 454

  Fly   228 PSAQLPPISGDEYGNMDANDREVAKSFARYRPKRRERGSIVRVHVTRIVSHAEFYARF--ADGPT 290
            .:..:||            |...||...|..|  .:..::|.|.|..|:|.::||.|.  .|...
  Rat   455 ANHDIPP------------DAVRAKKLCRLPP--LDTSTLVGVFVEYIISPSQFYVRIYSRDSSE 505

  Fly   291 VPTWSKSVMKRGTGDFRVWDIVLAP--------------------YQGRYHR---AKIVDIFRCR 332
            :.......|:|...:..|.|..:.|                    |:...||   .|.|::|
  Rat   506 LLEDMMIEMRRCYSNQLVSDRYVMPEYFIQPGHLCCVRISEDKWWYRVIIHRILGKKEVEVF--- 567

  Fly   333 YRVYFLDFGITEYTSKKNLTF---CYELEKAQH---NLAF---------RFEILGTRRQCPI-PY 381
                :.|||......|.:|.|   ||....||.   :||:         ...||..::.|.: |.
  Rat   568 ----YPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTSKAILHFQKLCGLKPL 628

  Fly   382 INI----LEGIKHLEHTVLRSDINVRIHNILKDGGYVI 415
            :.:    ::||.::......|:.:|..|::|:..|:.|
  Rat   629 VGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAI 666

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	12/63 (19%)
Tdrd5	XP_006250099.1	LOTUS_1_TDRD5	4..98	CDD:193599
		LOTUS_2_TDRD5	127..196	CDD:193589
		LOTUS_3_TDRD5	292..365	CDD:193590	17/79 (22%)
		TUDOR	483..602	CDD:278965	29/125 (23%)
		TUDOR	537..583	CDD:119391	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900