Protein Alignment CG15042 and TDRD6

DIOPT Version :9

• Sequence 1: NP_573308.1
• Gene: CG15042 / 32844
• FlyBaseID: FBgn0030937
• Length: 436
• Species: Drosophila melanogaster
• Sequence 2: NP_001010870.1
• Gene: TDRD6 / 221400
• HGNCID: 21339
• Length: 2096
• Species: Homo sapiens
• Alignment Length: 418
• Identity: 83/418 - (19%)
• Similarity: 155/418 - (37%)
• Gaps: 118/418 - (28%)

  Fly    54 HMRSVVGTFYKITDQIGEIA-IGTKLTGTVLLESLPVFYVTINGP----GSKLLKCLAMGQVQLQ 113
            |:..:...:.::.:...||: :..:|..   :::.|.:||   ||    |..:........:..:
Human  1313 HINDLSDFYVQLIEDEAEISHLSERLNS---VKTRPEYYV---GPPLQRGDMICAVFPEDNLWYR 1371

  Fly   114 EL--EQLP---------DYGEIFAFYDKAENRISRIAINAPVHPMGYCAYMIDAAKYTNMSGMER 167
            .:  ||.|         |||.:...:   .|:|.|:.:...:.| |.|.       :.::.|
Human  1372 AVIKEQQPNDLLSVQFIDYGNVSVVH---TNKIGRLDLVNAILP-GLCI-------HCSLQG--- 1422

  Fly   168 IFALPD--DLKKL--------PALTIKCRLVN--------VAQMHIFITQNV--RLRVLGSNGLE 212
             |.:||  :.||:        ....|:|..|.        :|..|..|..::  |..:...:.:|
Human  1423 -FEVPDNKNSKKMMHYFSQRTSEAAIRCEFVKFQDRWEVILADEHGIIADDMISRYALSEKSQVE 1486

  Fly   213 LLVALIRNRTNIRKIPSAQLPPISGDEYGNMDANDREVAKSFARYRPKRRERGSIVRVHVTRIVS 277
            |...:|::.::                 .:::.:|.:.:.....|.|:::    ::|.:.|.|..
Human  1487 LSTQVIKSASS-----------------KSVNKSDIDTSVFLNWYNPEKK----MIRAYATVIDG 1530

  Fly   278 HAEFYARFADGPTVPTWSKSVMKRG--TGDFRVWDIVLAPY-----------QGRYHRAKIVDIF 329
            ...|:.:|||...:......|...|  ..|.|  :.:..||           .|.|:||.|.:|
Human  1531 PEYFWCQFADTEKLQCLEVEVQTAGEQVADRR--NCIPCPYIGDPCIVRYREDGHYYRALITNI- 1592

  Fly   330 RCR---YRVYFLDFGITEYTSKKNLTFCYELEKAQHNLAFRFEILGTRRQ---CPIPYINILEGI 388
             |.   ..|..:|||        |:..|.: .||.  .|...|:|....|   |.:...||.||:
Human  1593 -CEDYLVSVRLVDFG--------NIEDCVD-PKAL--WAIPSELLSVPMQAFPCCLSGFNISEGL 1645

  Fly   389 KHLE-----HTVLRSDI-NVRIHNILKD 410
            ...|     :.::..|: .:.|..|.:|
Human  1646 CSQEGNDYFYEIITEDVLEITILEIRRD 1673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	13/54 (24%)
TDRD6	NP_001010870.1	TUDOR	<69..133	CDD:278965
		TUDOR	246..380	CDD:278965
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	287..316
		TUDOR	314..360	CDD:119391
		TUDOR	483..604	CDD:278965
		TUDOR	541..585	CDD:119391
		TUDOR	770..886	CDD:278965
		TUDOR	821..866	CDD:119391
		TUDOR	982..1102	CDD:278965
		TUDOR	1037..1080	CDD:119391
		TUDOR	1301..1422	CDD:278965	22/125 (18%)
		TUDOR	1356..1401	CDD:119391	8/47 (17%)
		TUDOR	1516..1638	CDD:278965	34/140 (24%)
		TUDOR	1571..>1609	CDD:119391	12/47 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000