DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15042 and Tdrd5

DIOPT Version :9

Sequence 1:NP_573308.1 Gene:CG15042 / 32844 FlyBaseID:FBgn0030937 Length:436 Species:Drosophila melanogaster
Sequence 2:NP_001128213.1 Gene:Tdrd5 / 214575 MGIID:2684949 Length:1040 Species:Mus musculus


Alignment Length:497 Identity:107/497 - (21%)
Similarity:173/497 - (34%) Gaps:145/497 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 FNLMKTE-SIPSCLLQPIRAVPKCVNSKEILSSLARNP-----RKSRLYPPHGGHMRSVVGTFYK 64
            |.:||.. |.|...::|         .|::| |:|:.|     ..|||  .|...:..:..||..
Mouse   228 FPVMKAHFSQPISNMEP---------PKQVL-SMAKTPTFNSVEASRL--NHTEKLNQLESTFKS 280

  Fly    65 ITDQIGEIAIGTKLTGTVLLE-SLPVFYVTINGPG----SKLLKCLAMGQVQLQELEQLPD---- 120
            :..|||.       .|||..| ...:.:|....|.    ||||     |:.:|...|||..    
Mouse   281 VIAQIGP-------GGTVDPELKRKIQFVVSKFPQGLFISKLL-----GEFELTFKEQLSPKQLG 333

  Fly   121 ----------YGEIFAFYDKAENRISRIAINAPVHPM----------GYCAYMIDAAKYTN--MS 163
                      ..:|.. .:.:|.|...:..:|.:.|:          ..|....|.....|  .|
Mouse   334 FLNVTELVGALSDILR-VEFSEERQDLLVFDADLKPLPSGGPLSSVRNSCLVQPDKKTEANPWTS 397

  Fly   164 GMERIFALPDDLKKLPALTIK-----CRLVNVAQMHIFITQNVRLRVLGSNGLELLVALIRNRTN 223
            .:.|        ..|..:.:|     |.|.|..:....|.:...|.|   ..|:|.|...:.:.:
Mouse   398 SLSR--------NSLSTVAVKKTTWDCPLKNQKEPEQKIYKKPNLVV---KPLQLQVETNKPQLS 451

  Fly   224 IRKIPSAQLPPISGDEYGNMDANDREVAKSFARYRPKRRERGSIVRVHVTRIVSHAEFYARF--A 286
            : .:.:..:||            |...||...|..|  .:..::|.|.|..|:|.::||.|.  .
Mouse   452 L-SVANHDIPP------------DAVRAKKLCRLPP--LDTSTLVGVFVEYIISPSQFYIRIYSR 501

  Fly   287 DGPTVPTWSKSVMKRGTGDFRVWDIVLAP--------------------YQGRYHR---AKIVDI 328
            |...:.......|:|...:..|.|..:.|                    |:...||   .|.|::
Mouse   502 DSSELLEDMMIEMRRCYSNQLVSDRYIMPEYFIQPGHLCCVKISEDKWWYRVIIHRILGKKEVEV 566

  Fly   329 FRCRYRVYFLDFGITEYTSKKNLTF---CYELEKAQH---NLAF---------RFEILGTRRQCP 378
            |       :.|||......|.:|.|   ||....||.   :||:         ...||..::.|.
Mouse   567 F-------YPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRPAEEHWTARAILHFQKLCG 624

  Fly   379 I-PYINI----LEGIKHLEHTVLRSDINVRIHNILKDGGYVI 415
            : |.:.:    ::||.::......|:.:|..|::|:..|:.|
Mouse   625 LKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAI 666

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15042NP_573308.1 TUDOR 310..351 CDD:119391 12/63 (19%)
Tdrd5NP_001128213.1 LOTUS_1_TDRD5 4..98 CDD:193599
LOTUS_2_TDRD5 127..196 CDD:193589
LOTUS_3_TDRD5 292..365 CDD:193590 15/78 (19%)
TUDOR 483..602 CDD:278965 29/125 (23%)
TUDOR 537..583 CDD:119391 10/52 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 857..891
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 912..975
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1525
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.