DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and tdrd6

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	XP_031758870.1	Gene:	tdrd6 / 105948404	XenbaseID:	XB-GENE-5969988	Length:	2499	Species:	Xenopus tropicalis

Alignment Length:	421	Identity:	87/421 - (20%)
Similarity:	157/421 - (37%)	Gaps:	114/421 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 SKEILSSLARNPRKSRLYPPHGGHMRSVVGTFYKITDQI-----------GEIAIGTKLTGTVLL 84
            |:|.:.||.:.|.:: .|.|........:.|||.:..:.           ||.|  ||.  :.::
Frog   467 SQEDVKSLPQTPPEA-FYVPTVPVAELNISTFYDVLVEFVADPSNFWIRTGENA--TKY--SEMM 526

  Fly    85 ESLPVFYVTINGPGSKLLKCLAMGQVQLQELEQLPDYGEIFA--FYDKAENRISRIAINAPVHPM 147
            |.:...|       ||..|        |..:...|..|::..  |.|....|...:||...:..:
Frog   527 EQIAALY-------SKASK--------LDGIMTTPMAGQLCCTKFKDDRFYRAEIVAIKGKMVEV 576

  Fly   148 GYCAYMIDAAKYTNMSGMERIFALPDDLKKLPALTIKCRLVN-------------VAQMHIFITQ 199
                |.||... |.:.....:..||.:|.::|.|.|.|.:.:             :|.....:.:
Frog   577 ----YFIDHGN-TELVDWYNVKKLPAELGEMPGLAIYCSVADTYPLGDSWSPEAILAFKMAVVDK 636

  Fly   200 NVRLRVLGSNGLELLVALIRN----RTNIRKIPSA-------QLPPISGDEYGNMDANDREVAKS 253
            .:.:.||.....:.::.::.|    :.::.||.||       ::.|:: ...|.....||::.:.
Frog   637 RLVIYVLSKEHNKYIIEVLDNSRIEQRSVGKILSAVGHAKYEEVEPVA-QHPGTTSDIDRKMQQQ 700

  Fly   254 FARYRP------KRRERGSIVRVHVTRIVSHAEFYARFAD-GPTVPT-----------WSKSVMK 300
            |:.:..      |.|::..:..|...:...::.|..:|.: |.|:..           |.::.:.
Frog   701 FSGHLNKDISLLKARQKEVVCSVQENKSEPYSPFEDQFFEPGTTIEVVVSCIINPSLFWCQNALH 765

  Fly   301 RGTGD---FRVWDIVL---APYQ-------------GRYHRAKIVDIFRC------RYRVYFLDF 340
            ....:   .::.||.|   ..|:             ||::||.||:....      ...|.|:|:
Frog   766 SAKLEKLMAKIQDICLNAGCSYERGACACLAKSSCDGRWYRAFIVNEMPAGKASSDHVEVLFVDY 830

  Fly   341 GITEYTSKKNLTFCYELE----KAQHNLAFR 367
            ||.|..|.|:|. |.|.|    |||   ||:
Frog   831 GIRETVSLKDLR-CMESELFGLKAQ---AFK 857

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	18/62 (29%)
tdrd6	XP_031758870.1	Tudor_SF	24..153	CDD:413384
		Tudor_TDRD6_rpt2	258..389	CDD:410492
		Tudor_SF	497..630	CDD:413384	32/156 (21%)
		Tudor_SF	734..863	CDD:413384	32/128 (25%)
		Tudor_SF	950..1073	CDD:413384
		Tudor_SF	1371..1483	CDD:413384
		Tudor_SF	1578..1717	CDD:413384
		MDN1	<1950..2492	CDD:227596
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100