DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15042 and tdrd7b

DIOPT Version :9

Sequence 1:	NP_573308.1	Gene:	CG15042 / 32844	FlyBaseID:	FBgn0030937	Length:	436	Species:	Drosophila melanogaster
Sequence 2:	NP_001340858.1	Gene:	tdrd7b / 100004703	ZFINID:	ZDB-GENE-150109-14	Length:	1085	Species:	Danio rerio

Alignment Length:	362	Identity:	71/362 - (19%)
Similarity:	131/362 - (36%)	Gaps:	97/362 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 NPRKSRLY----PPHGGHMRSVVGTFYKITDQIGEIAIGTKLTGTVLLESLPVFYVTINGPGSKL 101
            ||:::.||    .....:...:.|...|:..::....:...:...|  |...|..|..:.....:
Zfish   400 NPKRAILYAKVVEDENRNQSGLAGQEMKLERRLSSQTVPPLVIPRV--EYPSVLVVDASDTNCVI 462

  Fly   102 LKCLAMGQVQLQE-LE----------------QLPDYGEIFAFYDKAENRISRIAINAPVHPMGY 149
            |:.:..|..:.|| ||                :.|..|::.|...:.|:.|.|..:
Zfish   463 LRYIGEGYSKAQEKLEDEMREFYRQDNTKMALRSPSPGQLTAVGAEEEDDIIRAQV--------- 518

  Fly   150 CAYMIDAAK-------YTNMSGMERIFALPDDLKKLPALTIKCRLVNVAQMHIFITQNVRLRVLG 207
            |..|.|..|       ::.:..:.::|.|.:...:||....||:|   |.:..|..:...|:.|.
Zfish   519 CEVMADKVKVYYVDHGFSEVISIRKLFELNEKFYRLPFQATKCKL---AGLESFSQEQAVLKKLE 580

  Fly   208 SNGL-ELLVALIRNRTNIRKIPSAQLPPISGDEYGNMDA------NDREVAKSFARYRPKRRERG 265
            |... ::|:|.|..|.:   :|...|...|.|:..|::|      .||.:....       :...
Zfish   581 SIATGKILLAEILERED---MPLVVLYDTSQDDDVNINAACMKALQDRSLESPL-------KVNS 635

  Fly   266 SIVRVHVTRIVSHAEFYARFADGPTVPT---------------------WSKSVMKR---GTGDF 306
            :.:.|.||.:.|....|.:      ||:                     .|:|::.|   |..
Zfish   636 AYMNVSVTSVCSDGTIYCQ------VPSRGLTKLNEILEKTENYFHSQVTSESLVSRPFCGKN-- 692

  Fly   307 RVWDIVLAPYQGRYHRAKIVDIFRCR-YRVYFLDFGI 342
                 .||.|:|::.|.:|.::...| ..:.|:|.|:
Zfish   693 -----CLARYKGKWSRVEITNLHGSRVLDILFVDVGV 724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15042	NP_573308.1	TUDOR	310..351	CDD:119391	10/34 (29%)
tdrd7b	NP_001340858.1	LOTUS_1_TDRD7	4..91	CDD:193600
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..183
		Retinal	<160..342	CDD:330657
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..228
		LabA_like_C	232..297	CDD:326367
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..341
		LOTUS_3_TDRD7	341..408	CDD:193588	3/7 (43%)
		TUDOR	442..565	CDD:306940	27/136 (20%)
		TUDOR	636..758	CDD:306940	21/102 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	843..888
		TUDOR	897..1013	CDD:306940
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.000