Protein Alignment HisRS and GCN2

DIOPT Version :10

• Sequence 1: NP_573305.2
• Gene: HisRS / 32841
• FlyBaseID: FBgn0027087
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001190135.1
• Gene: GCN2 / 825110
• AraportID: AT3G59410
• Length: 1265
• Species: Arabidopsis thaliana
• Alignment Length: 602
• Identity: 154/602 - (25%)
• Similarity: 264/602 - (43%)
• Gaps: 113/602 - (18%)

  Fly     5 REQILEQIKVQGDLVRQLKAAKESKEKT-------APSGGGRVSSS-----GVPAQRQQQ--QQP 55
            |..||..:|::|:|  .||...|..|:.       :||...|.|::     ..|.:.:.:  ...
plant   704 RHVILTNLKLKGEL--PLKWVNEFPEQASLLRRLMSPSPSDRPSATELLKHAFPPRMESELLDNI 766

  Fly    56 QKQQQAQVQQQQHEQLHQI--DEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLR 118
            .:..|.......::::..:  ||||..:.:.:::          :..|........|......||
plant   767 LRIMQTSEDSSVYDRVVSVIFDEEVLEMKSHQSS----------RSRLCADDSYIQYTEINTELR 821

  Fly   119 QGVLDKIVQVFKRHGGEAI---------DTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRY 174
            ..|::...:||::|..:.:         |.|.|..|.|         ||:    ..||::|.:.|
plant   822 DYVVEITKEVFRQHCAKHLEVIPMRLLSDCPQFSRKTV---------KLL----TNGGDMLELCY 873

  Fly   175 DLTVPLARYLAMNKISSIKRYHIAKVYRR------DNPAMTKGRYREFYQCDFDI-AGTYDPMLP 232
            :|.:|...::::|:.||.|||.|:.||||      .||.:         |.|||| .||..  |.
plant   874 ELRLPFVHWISVNQKSSFKRYEISHVYRRAIGHSPPNPCL---------QADFDIVGGTLS--LT 927

  Fly   233 DAECVKIVSEILDTLDI---GDYVIKLNHRQLLDGMFQACGVPADSFRTICSAVDKLD------- 287
            :||.:|::.:|  |..|   |...|.|||..|||.::...|:.|:..|.:...:..:.
plant   928 EAEVLKVIVDI--TTHIFHRGSCDIHLNHGDLLDAIWSWAGIKAEHRRKVAELLSMMGSLRPQSS 990

  Fly   288 --KSPWADVRKEMVDEKGLDEAAADRIGEYV-RLSGGAELVEQLLANEK--LKAVPNAVKGLEGM 347
              |..|..:|::::.|..|.||..:|:.... |..|.|   :|.|...:  |:|.....|.|:.:
plant   991 ERKLKWVFIRRQLLQELKLPEAVVNRLQTVASRFCGDA---DQALPRLRGALRADRPTRKALDEL 1052

  Fly   348 KQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPAKTSQQNGEQANEPATV 412
            ..||.|..::.:::.|..|:.:.....|:..:.::..|            |.:.:...:|:...
plant  1053 SNLLTYLRVWRIEEHVHIDVLMPPTESYHRNLFFQVFL------------TKENSSGTSNDGVL- 1104

  Fly   413 GSVAGGGRYDNLV-GMFDPRGKA-VP-CVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYVAS- 473
              :|.|||||.|| .:.|...|. :| .||||:.:|.||..|.........::.||   |.|.|
plant  1105 --LAVGGRYDWLVQEVCDREHKMNLPGAVGVSLALETIFQHLPMDLRPIRNEVSTS---VLVCSR 1164

  Fly   474 AHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQG---LVK 535
            ...||..||::::..||:..:|||.....:|.|..|.::..||:|..:|::.::.:||.   .||
plant  1165 GGGGLLVQRMELVAELWEKSIKAEFVPTPDPSLTEQYEYANEHEIKCLVIITESGVAQNQIEFVK 1229

  Fly   536 LREVTTREETNVKLEDL 552
            :|.:..::|..|..|:|
plant  1230 VRHLELKKEKVVGREEL 1246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:469733	19/101 (19%)
		PLN02972	<102..559	CDD:215525	133/489 (27%)
GCN2	NP_001190135.1	RWD_RNF25	67..170	CDD:467654
		STKc_EIF2AK4_GCN2_rpt2	442..753	CDD:270948	14/50 (28%)
		PLN02972	<820..1250	CDD:215525	132/474 (28%)