Protein Alignment HisRS and HRS1

DIOPT Version :9

• Sequence 1: NP_573305.2
• Gene: HisRS / 32841
• FlyBaseID: FBgn0027087
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_190196.1
• Gene: HRS1 / 823753
• AraportID: AT3G46100
• Length: 486
• Species: Arabidopsis thaliana
• Alignment Length: 498
• Identity: 139/498 - (27%)
• Similarity: 226/498 - (45%)
• Gaps: 75/498 - (15%)

  Fly    80 RLLALKATLGGDA----APT------NQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGG 134
            ||:...|..||.:    ||.      ::|..:..||||||:.|:.|.||..:.:...:|.:.:|.
plant    38 RLICAAANGGGRSGSIVAPLVTEEDFHKKIDVNPPKGTRDFPPEDMRLRNWLFNHFKEVSRLYGY 102

  Fly   135 EAIDTPVFELKEVLTGKYGEDSK-LIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSI----KR 194
            |.:|.||.|.:.:...|.||:.: .:|..:|:|...:::|.:||..||| |.:.|..|:    |.
plant   103 EEVDYPVLETEALFIRKAGEEIRDQLYCFEDRGNRRVALRPELTPSLAR-LVIQKGKSVSLPLKW 166

  Fly   195 YHIAKVYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDI--GDYVIKLN 257
            :.|.:.:|.:.  ||:||.||.||.:.||.|. ..:..:||.:..:......:.|  .|...|::
plant   167 FAIGQCWRYER--MTRGRRREHYQWNMDIIGV-PQVTAEAELISSIVTFFKRIGITASDVGFKVS 228

  Fly   258 HRQLLDGMFQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGA 322
            .|::|..:.:..|||.|.|..:|..:||::|.|..:::||: ...|:.|.|
plant   229 SRKVLQELLKKYGVPEDLFGRVCIIIDKIEKIPIDEIKKEL-GFTGISEDA-------------- 278

  Fly   323 ELVEQLLANEKLKA-------VPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVI 380
              :||||....:|:       :..|.:.:..:|||......||..:.:.||.|:.|||.||||::
plant   279 --IEQLLQVLSVKSLDDLEDIIGGAGEAIADLKQLFSLAEKFGYSEWIQFDASVVRGLAYYTGIV 341

  Fly   381 YEGV-LKGESATVASPAKTSQQNGEQANEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGV 444
            :||. .||:                       :.::.||||||.|:..:.  |...|..|...|.
plant   342 FEGFDRKGK-----------------------LRAICGGGRYDRLLSTYG--GDDFPACGFGFGD 381

  Fly   445 ERIFSVLEARAAASGLKLRTSDVEVYVASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQ 509
            ..|..:|:.:.....|   ..:||..|.:..|.|......|...|.|.|...:...:..|...|.
plant   382 AVIVELLKEKDLLPEL---GQEVENIVCALDKDLQGAAATVATALRDKGQTVDLVLESKPLKWVF 443

  Fly   510 LQHCEEHQIPLVVVLGDAELAQGLVKLREVTTREETNVKLEDL 552
            .:....:...||:| |..|...|.|.::.:::.|:..|||.||
plant   444 KRAARVNARRLVLV-GKTEWEDGSVSVKVLSSGEQFQVKLSDL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:294248	5/11 (45%)
		HisS	98..561	CDD:223202	132/470 (28%)
		HisRS-like_core	114..452	CDD:238396	98/352 (28%)
		HisRS_anticodon	467..557	CDD:238436	24/86 (28%)
HRS1	NP_190196.1	PLN02530	2..486	CDD:178145	139/498 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	157	1.000	Inparanoid score	I1662
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1065556at2759
OrthoFinder	1	1.000	-	-		FOG0001634
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100351
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.730