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Protein Alignment HisRS and Hars2

DIOPT Version :9

Sequence 1:	NP_573305.2	Gene:	HisRS / 32841	FlyBaseID:	FBgn0027087	Length:	564	Species:	Drosophila melanogaster
Sequence 2:	NP_542367.1	Gene:	Hars2 / 70791	MGIID:	1918041	Length:	505	Species:	Mus musculus

Alignment Length:	482	Identity:	261/482 - (54%)
Similarity:	348/482 - (72%)	Gaps:	16/482 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 KATLGGDAAPTNQK---FTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGEAIDTPVFELKE 146
            ||.|..:...::|:   |.:|.||||||..||||.:|:.:||||:..|||||.:.:|||.|||||
Mouse    37 KAVLTSEQLKSHQEKPNFVIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKE 101

  Fly   147 VLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKVYRRDNPAMTKG 211
            :||.||.::..|:|||||||||:||:|||||||.||||||||:..:|||.:.||:||::||:.:|
Mouse   102 MLTEKYEDNFGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKLKKMKRYQVGKVWRRESPAIAQG 166

  Fly   212 RYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGMFQACGVPADSF 276
            |||||.||||||||.:|||:|||||::|:.|||..|.:||::||:|.|:::||:|..||||....
Mouse   167 RYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGIFAVCGVPESKL 231

  Fly   277 RTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLANEKLKAVPNAV 341
            |||||::|||||..|..||.|||.:|||....|||||::|:..||..|||.|..:.:|.....|:
Mouse   232 RTICSSMDKLDKMSWEGVRHEMVAKKGLAPEVADRIGDFVQYHGGISLVEDLFKDPRLSQSQLAL 296

  Fly   342 KGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPAKTSQQNGEQA 406
            :||..:|.|.:|..:||:..::|.|||||||||||||||||.||      :.|||:..:
Mouse   297 QGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVL------LESPAQAGK------ 349

  Fly   407 NEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGVERIFSVLEARAAASGLKLRTSDVEVYV 471
             |..:|||||.||||||||..|||:|..|||||:||||||||.::|.:...||.|:||::.:|:|
Mouse   350 -ETLSVGSVAAGGRYDNLVAQFDPKGHHVPCVGLSIGVERIFYLVEQKMKMSGEKVRTTETQVFV 413

  Fly   472 ASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVVVLGDAELAQGLVKL 536
            |:..|...::|||::..|||||:|||..||.|||||.||.:||:..|||:|::|:.|..:|::||
Mouse   414 ATPQKNFLQERLKIIAELWDAGIKAEMLYKNNPKLLTQLHYCEKADIPLMVIIGEQERNEGVIKL 478

  Fly   537 REVTTREETNVKLEDLAAEIRRRQQAS 563
            |.|.:|||..:..|.|.|||::|...|
Mouse   479 RSVASREEVTINRESLVAEIQKRLSES 505

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.