Protein Alignment HisRS and hars

DIOPT Version :10

• Sequence 1: NP_573305.2
• Gene: HisRS / 32841
• FlyBaseID: FBgn0027087
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001289185.1
• Gene: hars / 447847
• ZFINID: ZDB-GENE-040912-152
• Length: 520
• Species: Danio rerio
• Alignment Length: 492
• Identity: 312/492 - (63%)
• Similarity: 376/492 - (76%)
• Gaps: 11/492 - (2%)

  Fly    71 LHQIDEEVARLLALKATLGGDAAPTNQKFTLKTPKGTRDYGPQQMTLRQGVLDKIVQVFKRHGGE 135
            :.||||||||||.|||.||||..  ...|.|||.||||||.|:||.:|:.|.:.|:..|||||.|
Zfish    35 ISQIDEEVARLLQLKAQLGGDEG--KHVFVLKTAKGTRDYNPKQMAIREKVFNIIINCFKRHGAE 97

  Fly   136 AIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRYHIAKV 200
            .||:|||||||.|||||||||||||||||||||:||:|||||||.|||||||||::|||||||||
Zfish    98 TIDSPVFELKETLTGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKITNIKRYHIAKV 162

  Fly   201 YRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDGM 265
            |||||||||:|||||||||||||||.||.|:|||||:|:|.|||..||:||:.||:|.|::||||
Zfish   163 YRRDNPAMTRGRYREFYQCDFDIAGQYDAMIPDAECLKLVYEILSELDLGDFRIKVNDRRILDGM 227

  Fly   266 FQACGVPADSFRTICSAVDKLDKSPWADVRKEMVDEKGLDEAAADRIGEYVRLSGGAELVEQLLA 330
            |..||||.:.||||||.||||||..|.:|:||||:||||.|..||||.:||.:.||.:|.|:||.
Zfish   228 FAICGVPDEKFRTICSTVDKLDKLAWEEVKKEMVNEKGLSEEVADRIRDYVSMQGGKDLAERLLQ 292

  Fly   331 NEKLKAVPNAVKGLEGMKQLLKYCSIFGLDKRVSFDLSLARGLDYYTGVIYEGVLKGESATVASP 395
            :.||.....|..|:..||.|..|..:|.:..:|.||||||||||||||||||.:|     |.|:|
Zfish   293 DPKLSQSKQACAGITDMKLLFSYLELFQITDKVVFDLSLARGLDYYTGVIYEAIL-----TQANP 352

  Fly   396 AKTS---QQNGEQANEPATVGSVAGGGRYDNLVGMFDPRGKAVPCVGVSIGVERIFSVLEARAAA 457
            |..|   :|||.: :...:|||||||||||.|||||||:|:.|||||||||:||:||::|.:|..
Zfish   353 APASTPAEQNGAE-DAGVSVGSVAGGGRYDGLVGMFDPKGRKVPCVGVSIGIERVFSIMEQKAEL 416

  Fly   458 SGLKLRTSDVEVYVASAHKGLHEQRLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCEEHQIPLVV 522
            |..|:||::.:|.||||.|.|.|:|||:...||:||:|||..||.|||||.||||||:..||||.
Zfish   417 SSEKVRTTETQVLVASAQKNLLEERLKLTAELWNAGIKAEVLYKKNPKLLSQLQHCEDTGIPLVA 481

  Fly   523 VLGDAELAQGLVKLREVTTREETNVKLEDLAAEIRRR 559
            :||:.||..|:||||.|.:|||.:|...:|..|:::|
Zfish   482 ILGEQELKDGVVKLRNVASREEVDVPRAELVDEVKKR 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:469733	16/20 (80%)
		PLN02972	<102..559	CDD:215525	292/459 (64%)
hars	NP_001289185.1	S15_NS1_EPRS_RNA-bind	<37..56	CDD:469733	16/18 (89%)
		PLN02972	<64..518	CDD:215525	292/459 (64%)