Protein Alignment HisRS and Eif2ak1

DIOPT Version :9

• Sequence 1: NP_573305.2
• Gene: HisRS / 32841
• FlyBaseID: FBgn0027087
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: XP_038945063.1
• Gene: Eif2ak1 / 27137
• RGDID: 70883
• Length: 645
• Species: Rattus norvegicus
• Alignment Length: 423
• Identity: 81/423 - (19%)
• Similarity: 142/423 - (33%)
• Gaps: 106/423 - (25%)

  Fly   136 AIDTPVFELKEVLTGKYGEDSKLIYDLKDQGGEILSMRYDLTVPLARYLAMNKISSIKRY-HIAK 199
            |||.|.    ||...||.|        .|...|:...:..|..|...:|..|::..:... |::.
  Rat    26 AIDFPA----EVSDPKYDE--------SDVPAELQVFKEPLQQPTFPFLVANQLLLVSLLEHLSH 78

  Fly   200 VYRRDNPAMTKGRYREFYQCDFDIAGTYDPMLPDAECVKIVSEILDTLDIGDYVIKLNHRQLLDG 264
            |: ..||..:|..::...|....:.     :|....|....|.           ::|:|.:.:..
  Rat    79 VH-EPNPLHSKQVFKLLCQTFIKMG-----LLSSFTCSDEFSS-----------LRLHHNRAITH 126

  Fly   265 MFQACGVPADSFRTICSAVDKLDKSPWAD---VRKEMVDEKGLDEAAADRIGEYV---------- 316
            :.:             ||.:::.:.|..|   ::|....|..|:...:..:.|:.
  Rat   127 LMR-------------SAKERVRQDPCQDNSYMQKIRSREIALEAQTSRYLNEFEELAILGKGGY 178

  Fly   317 --------RLSGGAELVEQLLANEKLKA----VPNAVKGLEGMKQ---------LLKYCSIFGLD 360
                    :|.|....::::|.....|.    |...||.|.|::.         .:::..:....
  Rat   179 GRVYKVRNKLDGQHYAIKKILIKSATKTDCMKVLREVKVLAGLQHPNIVGYHTAWIEHVHVLQPQ 243

  Fly   361 KRVSFDLSLARGLDYYTGVIYEGVLKGESATVASPAKTSQQNGEQANEPATVGSVAGGGRYDNLV 425
            .||...|.....|..:.|...:|.:|...:  :|....::...|:.| |.....|.  ...:|||
  Rat   244 DRVPIQLPSLEVLSEHEGDRNQGGVKDNES--SSSIIFAELTPEKEN-PLAESDVK--NENNNLV 303

  Fly   426 GMFDPRGKAVPCVGVSIGVERIFSVLEARAAASGLKL---------RTSDVEVYVASAHKGLHEQ 481
            ..     :|...:..|...|....:.|.....|.|:.         .:||||....|..:...:.
  Rat   304 SY-----RANLVIRSSSESESSIELQEDGLNESPLRPVVKHQLPLGHSSDVEGNFTSTDESSEDN 363

  Fly   482 RLKVLNLLWDAGVKAEHSYKLNPKLLVQLQHCE 514
                ||||.    :.|..|.|  .|.:|:|.||
  Rat   364 ----LNLLG----QTEARYHL--MLHIQMQLCE 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisRS	NP_573305.2	S15_NS1_EPRS_RNA-bind	6..92	CDD:294248
		HisS	98..561	CDD:223202	81/423 (19%)
		HisRS-like_core	114..452	CDD:238396	61/350 (17%)
		HisRS_anticodon	467..557	CDD:238436	15/48 (31%)
Eif2ak1	XP_038945063.1	STKc_EIF2AK1_HRI	160..604	CDD:270951	48/247 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0124
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900