DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ggt-1 and si:dkey-222h21.12

DIOPT Version :9

Sequence 1:	NP_001285408.1	Gene:	Ggt-1 / 32839	FlyBaseID:	FBgn0030932	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_021333865.1	Gene:	si:dkey-222h21.12 / 795959	ZFINID:	ZDB-GENE-090312-33	Length:	605	Species:	Danio rerio

Alignment Length:	545	Identity:	203/545 - (37%)
Similarity:	295/545 - (54%)	Gaps:	58/545 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AVVSNGIGCAAVGGEMLTDGGSAVDAAIATLLCEGLLLPHSMGIGGGFVATIYTRSSRKVETVIA 106
            ||.::...|:.:|.::|...|||||||||.|||..::.|.|||||||.|.|||...:..||.:.|
Zfish    41 AVAADAEICSKIGRDILGRNGSAVDAAIAALLCVSVINPQSMGIGGGSVFTIYNAINGTVEIINA 105

  Fly   107 RESAPAAAHKDMFVGETSITGAKSG-----AVPGEILGYWEMHRRYGILPWKRLFEPSIKLAREG 166
            ||:||.:|..:||...|.    |..     |||||:.||...|.|||.||||.|||||||||.||
Zfish   106 RETAPMSATANMFDNNTQ----KENPGLLIAVPGELRGYKMAHDRYGKLPWKDLFEPSIKLASEG 166

  Fly   167 HVVSRYLAAAIQSKLDNIKADPGLSAVFLNATGDPHLEGDYMKRPALADTLERIAENGAKEFYDG 231
            ..:|:.||.||..:...|:.:..|..||.::...|..|.::.:.|.||.|...|||.|...||||
Zfish   167 FNISKGLAYAINMEERKIRKNIALREVFCDSDNKPLKESNFTRFPKLAKTYRTIAEEGPDAFYDG 231

  Fly   232 GETGRKFVEDIQKMGGIITEQDLRDYTVRWESDGHVSAHVSGTYTLYSTPMPSSGPVLAFILNLM 296
            ..| :..:::|...||.||.:||:.|  :.:...:......|.|..::...|..|||||.|:.::
Zfish   232 SLT-QSILDEITVAGGNITREDLKRY--KPDLQKYALNFTVGKYIFFAPTAPFGGPVLALIMKIL 293

  Fly   297 ADLYT-------------------------DNEPIYWQRVVEAFKHAYGQRTNLGDMYADPVSAA 336
            ....|                         :|..:.:.|::|||:.|..|:..|    |||:...
Zfish   294 LGNGTAGSSKSHLLHYYSGFNLSNKSVSTPENMTLTYHRIIEAFRFANAQKAKL----ADPLHEK 354

  Fly   337 SINATLEEMLKPEFLESVRKLIHDNSTSEDYLYYGANFTVEEDHGTAHMNVLATNGDAVSITSTI 401
            ::...::.|....|.:::|..|.|:.....|...|... |.:||||:|::|:|.:|.||::||:|
Zfish   355 NVTEFVKYMTSDSFADNIRNKIKDDIKQTSYDEQGIKI-VPDDHGTSHLSVIAKDGSAVAVTSSI 418

  Fly   402 NNYFGSKVASTQTGIILNDEMDDFSTPGVINGFGVPASPANYIYPGKRPMSSMSPCIIVDQEG-N 465
            ||:|||.|.|...|||.||:|.|:::|.:.||       .|.|.|||||:|||.|.||:|::. .
Zfish   419 NNFFGSGVMSCLRGIIFNDQMSDYTSPEMKNG-------PNAIKPGKRPLSSMCPTIILDKDSRK 476

  Fly   466 VRLLVGAAGGTRITTSVAAVIMKYLLRKESLTAAVNNGRLHHQLAPMRVSYEQEVDSSVTDYLKQ 530
            ||::.|.||||.||||||.||:.:|....:|..||...|:  |:.|...:.|:..||:|..:|.:
Zfish   477 VRMVAGGAGGTNITTSVAQVILDHLYFDYNLQKAVAEPRV--QVPPNVTNVEEGFDSTVMGWLSR 539

  Fly   531 VGHEMYEEPVGSSFAAVTAIGALEQ 555
            ..|.:      |.:.::|.:..:|:
Zfish   540 KYHNI------SQYTSLTMVQVVEK 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ggt-1	NP_001285408.1	G_glu_transpept	56..566	CDD:279371	199/531 (37%)
si:dkey-222h21.12	XP_021333865.1	G_glu_transpept	55..570	CDD:307247	199/531 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579884
Domainoid	1	1.000	396	1.000	Domainoid score	I724
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1854
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		mtm6378
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770