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Protein Alignment Ggt-1 and GGT2

DIOPT Version :9

Sequence 1:	NP_001285408.1	Gene:	Ggt-1 / 32839	FlyBaseID:	FBgn0030932	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001338233.1	Gene:	GGT2 / 728441	HGNCID:	4251	Length:	574	Species:	Homo sapiens

Alignment Length:	565	Identity:	236/565 - (41%)
Similarity:	313/565 - (55%)	Gaps:	43/565 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KKLLLWLLLA---ALMVTALTLGLVFGLKNRDT-LYISGAVVSNGIGCAAVGGEMLTDGGSAVDA 67
            |||::..|||   .|::..|.|.|....|..|. :|...|:.::...|..:|.:.|.||||||||
Human     3 KKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAMAADAKQCLEIGRDTLRDGGSAVDA 67

  Fly    68 AIATLLCEGLLLPHSMGIGGGFVATIYTRSSRKVETVIARESAPAAAHKDMF-VGETSITGAKSG 131
            |||.|||.||:..||||||.|...|||..::.:.|.:.|||.||..|...|| ..|.|..|..|.
Human    68 AIAALLCVGLMNAHSMGIGVGLFLTIYNSTTHESEVINAREVAPRLAFASMFNSSEQSQKGGLSV 132

  Fly   132 AVPGEILGYWEMHRRYGILPWKRLFEPSIKLAREGHVVSRYLAAAIQSKLDNIKADPGL-----S 191
            ||||||.||...|:|:|.|||.|||:|||:|||:|..|.:.|||.:::|...|:..|.|     .
Human   133 AVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAVLENKRTVIEQQPVLCPLCPG 197

  Fly   192 AVFLNATGDPHL--EGDYMKRPALADTLERIAENGAKEFYDGGETGRKFVEDIQKMGGIITEQDL 254
            .||..   |..:  ||:.:..|.||||.|.:|..||:.||:|.... :.|:|||..|||:|.:||
Human   198 EVFCR---DRKVLREGERLTLPRLADTYEMLAIEGAQAFYNGSLMA-QIVKDIQAAGGIVTAEDL 258

  Fly   255 RDYTVRWESDGHVSAHVSGTYTLYSTPMPS---SGPVLAFILNLMADLYTDNEPI--------YW 308
            .:|  |.|...|......|...||   |||   ||||||.|||::.......|.:        .:
Human   259 NNY--RAELIEHPLNISLGDAVLY---MPSARLSGPVLALILNILKGYNFSRESVETPEQKGLTY 318

  Fly   309 QRVVEAFKHAYGQRTNLGD-MYADPVSAASINATLEEMLKPEFLESVRKLIHDNSTSEDYLYYGA 372
            .|:||||:.||.:||.||| .:.|      :...:..|....|...:|..|.|: |:....||..
Human   319 HRIVEAFRFAYAKRTLLGDPKFVD------VTEVVRNMTSEFFAAQLRSQISDH-TTHPISYYKP 376

  Fly   373 NFTVEEDHGTAHMNVLATNGDAVSITSTINNYFGSKVASTQTGIILNDEMDDFSTPGVINGFGVP 437
            .|...:|.||||::|:|.:|.|||.|||||.||||||.|..:||:.|:|....:.|...|.||.|
Human   377 EFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVCSPVSGILFNNEWTTSALPAFTNEFGAP 441

  Fly   438 ASPANYIYPGKRPMSSMSPCIIVDQEGNVRLLVGAAGGTRITTSVAAVIMKYLLRKESLTAAVNN 502
            .||||:|.|||:|:.||...|:|.|:|.||::|||||||:|||..|..|:..|.....:..||..
Human   442 PSPANFIQPGKQPLLSMCLTIMVGQDGQVRMVVGAAGGTQITTDTALAIIYNLWFGYDVKRAVEE 506

  Fly   503 GRLHHQLAPMRVSYEQEVDSSVTDYLKQVGHEMYEEPVGSSFAAV 547
            .|||::|.|...:.|:.:|.:||..|:...|   ...:.|:|.||
Human   507 PRLHNKLLPNVTTVERNIDQAVTAALETRHH---HTQIASTFIAV 548

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.