DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ggt-1 and ggt1a

DIOPT Version :9

Sequence 1:	NP_001285408.1	Gene:	Ggt-1 / 32839	FlyBaseID:	FBgn0030932	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_017212782.1	Gene:	ggt1a / 393387	ZFINID:	ZDB-GENE-040426-1388	Length:	619	Species:	Danio rerio

Alignment Length:	565	Identity:	246/565 - (43%)
Similarity:	334/565 - (59%)	Gaps:	32/565 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KKLLLWLLLAALMVTALTLGLVFGLKNR------DTLYISGAVVSNGIGCAAVGGEMLTDGGSAV 65
            |.|:..:::..:......||:..|:.|:      |..|...||.::...|:.||.::|...||||
Zfish    49 KSLVAGMVVLLVAAVGFFLGVYLGIGNKRLTVSSDHFYSKAAVAADAGKCSEVGRDILKRNGSAV 113

  Fly    66 DAAIATLLCEGLLLPHSMGIGGGFVATIYTRSSRKVETVIARESAPAAAHKDMFVGETSIT--GA 128
            ||:||.|||.||...||||||||...||:..|:.||||:.|||:||..|.:|||...|.::  |.
Zfish   114 DASIAALLCVGLFNAHSMGIGGGLFFTIFNASTGKVETIDARETAPKNASEDMFGNNTQLSRKGG 178

  Fly   129 KSGAVPGEILGYWEMHRRYGILPWKRLFEPSIKLAREGHVVSRYLAAAIQSKLDNIKADPGLSAV 193
            .|.|:||||.||...|.|:|.|||:.||.|||||||.|..|.:.||.||....:.|.:|..|..|
Zfish   179 LSIAIPGEIRGYEMAHNRHGRLPWRELFLPSIKLARNGFPVGKALANAIAKNKETILSDMTLCEV 243

  Fly   194 FLNATGDPHLEGDYMKRPALADTLERIAENGAKEFYDGGETGRKFVEDIQKMGGIITEQDLRDY- 257
            |.::..:...|.|.::...||||.|:|||.|...|| .|...:..|:|||..|||||.:|||:|
Zfish   244 FCDSDKNILKENDIIRFTTLADTYEKIAEEGPDVFY-SGSLAQNIVDDIQAAGGIITLEDLREYK 307

  Fly   258 TVRWESDGHVSAHVSGTYTLYSTPMPSSGPVLAFILNLMADL-YTDN-------EPIYWQRVVEA 314
            .|..|:...::.   |.||:.....||||||||.|||::... ::|:       :.:.:.|:|||
Zfish   308 PVLNETPLKLTV---GEYTINVPDAPSSGPVLALILNIVDGFNFSDHSVSTAEKKTLTYHRIVEA 369

  Fly   315 FKHAYGQRTNLGD-MYADPVSAASINATLEEMLKPEFLESVRKLIHDNSTSEDYLYYGANFTVEE 378
            |:.||.:|:.||| .|      .:|...:..|....|.:::|..|.|::|..| .||...:.|.:
Zfish   370 FRFAYAKRSKLGDPRY------LNITDLIHNMTSDYFADNIRSKITDDTTHPD-SYYDPEYFVPD 427

  Fly   379 DHGTAHMNVLATNGDAVSITSTINNYFGSKVASTQTGIILNDEMDDFSTPGVINGFGVPASPANY 443
            :|||||::|:|.:|.||:.|||||.||||||.|..||||.||||||||:|.:.||||||.||.|:
Zfish   428 NHGTAHLSVIAEDGSAVAATSTINLYFGSKVMSRSTGIIFNDEMDDFSSPYITNGFGVPPSPNNF 492

  Fly   444 IYPGKRPMSSMSPCIIVDQEGNVRLLVGAAGGTRITTSVAAVIMKYLLRKESLTAAVNNGRLHHQ 508
            |.|||||:|||.|.||.|:...|:::|||:|||:|||:.|.||:..|.....|..||...|:|:|
Zfish   493 IQPGKRPLSSMCPTIIFDKHNRVKMVVGASGGTKITTATALVILNSLFFNYDLKKAVTEPRVHNQ 557

  Fly   509 LAPMRVSYEQEVDSSVTDYLKQVGH--EMYEEPVGSSFAAVTAIG 551
            |.|.....||:.:.||.|.|:|..|  |:...| |:...|:...|
Zfish   558 LNPNMTVVEQDFEQSVLDGLEQKNHVTELQRTP-GAVVQAIVRQG 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ggt-1	NP_001285408.1	G_glu_transpept	56..566	CDD:279371	233/510 (46%)
ggt1a	XP_017212782.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579880
Domainoid	1	1.000	396	1.000	Domainoid score	I724
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1854
OMA	1	1.010	-	-		QHG58031
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	1	1.000	-	-		FOG0000229
OrthoInspector	1	1.000	-	-		mtm6378
orthoMCL	1	0.900	-	-		OOG6_100578
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R489
SonicParanoid	1	1.000	-	-		X210
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.940