DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ggt-1 and Ggt7

DIOPT Version :9

Sequence 1:	NP_001285408.1	Gene:	Ggt-1 / 32839	FlyBaseID:	FBgn0030932	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	XP_038960082.1	Gene:	Ggt7 / 156275	RGDID:	619870	Length:	674	Species:	Rattus norvegicus

Alignment Length:	555	Identity:	162/555 - (29%)
Similarity:	263/555 - (47%)	Gaps:	63/555 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLAALMVTALTLGLVFGLKNRDTLYISGAVVSNGIGCAAVGGEMLTDGGSAVDAAIATLLCEGL 77
            |..|..:..||.:.:.||   ...::..||||::...|.|:|.|:|:..||:||||:|..||.|:
  Rat   115 LTFATGVTVALVMQIYFG---DPQIFQQGAVVTDASCCTALGMEVLSKQGSSVDAAVAAALCLGI 176

  Fly    78 LLPHSMGIGGGFVATIYTRSSRKVETVIARESAPAAAHKDMF--VGETSITGAKSGAVPGEILGY 140
            :.|||.|:|||.|..::.....:...:..|||||.|..::..  ..:|..:.::....|.:...|
  Rat   177 VAPHSSGLGGGGVMLVHDIRRNESHLIDFRESAPGALREEALQRSWDTKDSPSQEPPFPQDPSSY 241

  Fly   141 WE--MHRRYG---ILPWKRLFEPSIKLAREGHVVSRYLAAAIQSKLDNIKADPGLSAVFLNA--- 197
            .:  :|....   .|||.::...:..:|::|..|:..||.|:..:|     .|..|..||..
  Rat   242 PQDLLHPLLSGPLRLPWSQVLAFAAAVAQDGFNVTHDLAHALAEQL-----PPNASDRFLETFLP 301

  Fly   198 TGDPHLEGDYMKRPALADTLERIAENGAKEFYDGGETGRKFVEDIQKMGGIITEQDLRDYTVRWE 262
            .|.|.|.|..::||.||:.|:.:..:|...||:||....:.|.::|..||::||:|..:|:...|
  Rat   302 LGHPPLPGSLLRRPDLAEVLDILGISGPAAFYNGGNLTLEMVAEVQHAGGVMTEEDFSNYSALTE 366

  Fly   263 SDGHVSAHVSGTY---TLYSTPMPSSGPVLAFILNL-----MADLYTDNEPIYWQRVVEAFKHAY 319
            ..      |.|.|   .:.|.|.|.:||.|...||:     :..|.:..:.::|  |.|..|.|.
  Rat   367 KP------VCGVYRGHLVLSPPPPHTGPALISALNILEGFNLTSLVSREQALHW--VAETLKIAL 423

  Fly   320 GQRTNLGDMYADPVSAASINATLEEMLKPEFLESVRKLIHDNSTSEDYLYYGANFTVEEDHG--- 381
            ...:.||    |||..::|:.::::||......:.|..|.|:..:...|     ..|.|..|
  Rat   424 ALASRLG----DPVYDSTISESMDDMLSKVEAANFRGHISDSQAAPAPL-----LPVYELDGAPT 479

  Fly   382 TAHMNVLATNGDAVSITSTINNYFGSKVASTQTGIILNDEMDDFSTPGVINGFGVPASPANYIYP 446
            .|.:.|:..:...|::.|::|..|||.:. |.:||:||.:|.|||.|........| |..|.:.|
  Rat   480 AAQVLVMGPDDFIVAMVSSLNRPFGSGLL-TPSGILLNSQMLDFSWPNRTANHSAP-SLENSVQP 542

  Fly   447 GKRPMSSMSPCIIVDQEG--NVRLLVGAAGGTRITTSVAAVIMKYLLRKESLTAAVNNGRLHHQL 509
            ||||:|.:.|.::...||  ...|.:||.|..|..:.:..|::..|....:|:.::..||||..|
  Rat   543 GKRPLSFLLPTVVRPAEGLCGTYLALGANGAARGLSGLTQVLLNVLTLNRNLSDSLARGRLHPDL 607

  Fly   510 APMRVSYEQEVDSSV---------TDYLKQVGHEM 535
            .    |...:|||..         .::|:..||.:
  Rat   608 Q----SNVLQVDSECRAGEFTEEEIEFLEARGHHV 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ggt-1	NP_001285408.1	G_glu_transpept	56..566	CDD:279371	149/512 (29%)
Ggt7	XP_038960082.1	G_glu_transpept	155..665	CDD:395806	149/512 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0405
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1419292at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11686
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850