back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ggt-1 and Ggt1

DIOPT Version :9

Sequence 1:	NP_001285408.1	Gene:	Ggt-1 / 32839	FlyBaseID:	FBgn0030932	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_446292.2	Gene:	Ggt1 / 116568	RGDID:	2683	Length:	568	Species:	Rattus norvegicus

Alignment Length:	559	Identity:	244/559 - (43%)
Similarity:	328/559 - (58%)	Gaps:	29/559 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KKLLLWLLLAALMVTALTLGLVFGLKNR----DTLYISGAVVSNGIGCAAVGGEMLTDGGSAVDA 67
            |...|.|.|.|:::..:.:||...|...    |.:|...||.::...|:.:|.:||.:|||.|||
  Rat     2 KNRFLVLGLVAVVLVFVIIGLCIWLPTTSGKPDHVYSRAAVATDAKRCSEIGRDMLQEGGSVVDA 66

  Fly    68 AIATLLCEGLLLPHSMGIGGGFVATIYTRSSRKVETVIARESAPAAAHKDMF-VGETSITGAKSG 131
            |||:|||.||:..||||||||...|||..::||.|.:.|||.||..|:..|| ..:.|..|..|.
  Rat    67 AIASLLCMGLINAHSMGIGGGLFFTIYNSTTRKAEVINAREMAPRLANTSMFNNSKDSEEGGLSV 131

  Fly   132 AVPGEILGYWEMHRRYGILPWKRLFEPSIKLAREGHVVSRYLAAAIQSKLDNIKADPGLSAVFLN 196
            ||||||.||...|:|:|.|||.|||:|||:|||.|..|.:.||.|:..|.|.|:..|.|..||..
  Rat   132 AVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLARALDKKRDIIEKTPALCEVFCR 196

  Fly   197 ATGDPHLEGDYMKRPALADTLERIAENGAKEFYDGGETGRKFVEDIQKMGGIITEQDLRDYTVRW 261
             .|....||:.:..|.|||||:.:|:.||:.||:|..|. :.|:|||:.|||:|.:||.:|  |.
  Rat   197 -QGKVLQEGETVTMPKLADTLQILAQEGARAFYNGSLTA-QIVKDIQEAGGIMTVEDLNNY--RA 257

  Fly   262 ESDGHVSAHVSGTYTLYSTPMPSSGPVLAFILNLMADLYT---------DNEPIYWQRVVEAFKH 317
            |...|..:...|..|||....|.|||||..|||::.. |.         :.:.:.:.|:||||:.
  Rat   258 EVIEHPMSIGLGDSTLYVPSAPLSGPVLILILNILKG-YNFSPKSVATPEQKALTYHRIVEAFRF 321

  Fly   318 AYGQRTNLGD-MYADPVSAASINATLEEMLKPEFLESVRKLIHDNSTSEDYLYYGANFTVEEDHG 381
            ||.:||.||| .:.|      ::..:..|....:...:|..|.| .|:....||...|.:.:|.|
  Rat   322 AYAKRTMLGDPKFVD------VSQVIRNMSSEFYATQLRARITD-ETTHPTAYYEPEFYLPDDGG 379

  Fly   382 TAHMNVLATNGDAVSITSTINNYFGSKVASTQTGIILNDEMDDFSTPGVINGFGVPASPANYIYP 446
            |||::|::.:|.||:.|||||.||||||.|..:||:.||||||||:|...|.|||..||||:|.|
  Rat   380 TAHLSVVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFTNQFGVAPSPANFIKP 444

  Fly   447 GKRPMSSMSPCIIVDQEGNVRLLVGAAGGTRITTSVAAVIMKYLLRKESLTAAVNNGRLHHQLAP 511
            ||:|:|||.|.||||::|.||::|||:|||:||||||..|:..|.....:..||...|||:||.|
  Rat   445 GKQPLSSMCPSIIVDKDGKVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLP 509

  Fly   512 MRVSYEQEVDSSVTDYLKQVGHEMYEEPVGSSFAAVTAI 550
            ...:.|:.:|..||..||...|  :.|......|.|.|:
  Rat   510 NTTTVEKNIDQVVTAGLKTRHH--HTEVTPDFIAVVQAV 546

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.