Protein Alignment Wnt5 and Wnt4

DIOPT Version :10

• Sequence 1: NP_476924.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_445854.1
• Gene: Wnt4 / 84426
• RGDID: 621348
• Length: 351
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 137/463 - (29%)
• Similarity: 198/463 - (42%)
• Gaps: 160/463 - (34%)

  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAP 612
            |....||...|.:.|.::..||.::..||:.||:|||:||:||||||||.:...|||.:.:....
  Rat    43 CEKLKGLIQRQVQMCKRNLEVMDSVRHGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTR 107

  Fly   613 EMAFIHALAAATVTSFIARACRDGQLASCSCSR---GSRPKQLHDDWKWGGCGDNLEFAYKFATD 674
            |.||::|:::|.|...:.|||..|.|..|.|.|   |..|:    .::|.||.||:.:...|:..
  Rat   108 EAAFVYAISSAGVAFAVTRACSSGDLEKCGCDRTVHGVSPQ----GFQWSGCSDNIAYGVAFSQS 168

  Fly   675 FIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEA 739
            |:|.||
  Rat   169 FVDVRE----------------------------------------------------------- 174

  Fly   740 ENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKN 804
                                                                             
  Rat   175 ----------------------------------------------------------------- 174

  Fly   805 QRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSG 869
                                      ||.....:|:|||||||||||:|::...|:.||||||||
  Rat   175 --------------------------RSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSG 213

  Fly   870 SCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRG---RLQIKDLQFKVPTAHDLIYLDESPD 931
            ||.:.|||:.:...|::|..|:||::|||:|:..:.|   .|..::.|||..|..||:||:.|||
  Rat   214 SCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPD 278

  Fly   932 WCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTK 996
            :|.........||.||.|:|.|..::.|.:||||||::|.::.:.|||.|:|||||.|||..|.:
  Rat   279 FCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAHVELAERCGCRFHWCCFVKCRQCQR 343

  Fly   997 VLEEHTCK 1004
            ::|.|||:
  Rat   344 LVEMHTCR 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_476924.1	Wnt_Wnt5	548..1004	CDD:381711	136/461 (30%)
Wnt4	NP_445854.1	Wnt_Wnt4	43..351	CDD:381710	136/461 (30%)