Protein Alignment Wnt5 and WNT5B

DIOPT Version :9

• Sequence 1: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: XP_024304971.1
• Gene: WNT5B / 81029
• HGNCID: 16265
• Length: 411
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 159/457 - (34%)
• Similarity: 225/457 - (49%)
• Gaps: 145/457 - (31%)

  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAP 612
            |....|||..|:|.|..:...|..|..||:..|:|||.||:.|||||||.::.:|||.:..:.:.
Human   100 CSQLPGLSPGQRKLCQLYQEHMAYIGEGAKTGIKECQHQFRQRRWNCSTADNASVFGRVMQIGSR 164

  Fly   613 EMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHDDWKWGGCGDNLEFAYKFATDFID 677
            |.||.||::||.|.:.|:||||:|:|::|.|||.:|||.|..||.|||||||:|:.|:||.:|:|
Human   165 ETAFTHAVSAAGVVNAISRACREGELSTCGCSRTARPKDLPRDWLWGGCGDNVEYGYRFAKEFVD 229

  Fly   678 SREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENS 742
            :||:|.|
Human   230 AREREKN---------------------------------------------------------- 236

  Fly   743 HILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRA 807
                                                           |.||.::
Human   237 -----------------------------------------------FAKGSEE----------- 243

  Fly   808 AADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCS 872
                                         :.|.||||.|||||||||.|.|.:.|||||||||||
Human   244 -----------------------------QGRVLMNLQNNEAGRRAVYKMADVACKCHGVSGSCS 279

  Fly   873 LITCWQQLSSIREIGDYLREKYEGATKVKINKRGRLQIKDLQFKVPTAHDLIYLDESPDWCRNSY 937
            |.|||.||:..|::||.|:|||:.|..:::.::|||::.:.:|..||..||:|:|.|||:|..:.
Human   280 LKTCWLQLAEFRKVGDRLKEKYDSAAAMRVTRKGRLELVNSRFTQPTPEDLVYVDPSPDYCLRNE 344

  Fly   938 ALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHT 1002
            :....||.||:|:|.|.|::.|.::|||||||....:..|||:|||||||.|:|:.||::::::.
Human   345 STGSLGTQGRLCNKTSEGMDGCELMCCGRGYNQFKSVQVERCHCKFHWCCFVRCKKCTEIVDQYI 409

  Fly  1003 CK 1004
            ||
Human   410 CK 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	155/449 (35%)
WNT5B	XP_024304971.1	wnt	102..411	CDD:306592	156/453 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152285
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003382
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2901
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.870