Protein Alignment Wnt5 and WNT10B

DIOPT Version :9

• Sequence 1: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_003385.2
• Gene: WNT10B / 7480
• HGNCID: 12775
• Length: 389
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 128/505 - (25%)
• Similarity: 178/505 - (35%)
• Gaps: 211/505 - (41%)

  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAA- 611
            |.:..|||..|...|:::..|..:..:|...|:.|||.|.:::|||||.....   |.:...:|
Human    48 CLTLSGLSKRQLGLCLRNPDVTASALQGLHIAVHECQHQLRDQRWNCSALEGG---GRLPHHSAI 109

  Fly   612 -----PEMAFIHALAAATVTSFIARACRDGQLASCSC---------------------SRG-SRP 649
                 .|.||..::.||.|...:|.||..|:|.||.|                     ||| |.|
Human   110 LKRGFRESAFSFSMLAAGVMHAVATACSLGKLVSCGCGWKGSGEQDRLRAKLLQLQALSRGKSFP 174

  Fly   650 KQL-------------HDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNR 701
            ..|             .|.|:||||..:::|..||:.||:||||.
Human   175 HSLPSPGPGSSPSPGPQDTWEWGGCNHDMDFGEKFSRDFLDSREA-------------------- 219

  Fly   702 MHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILT 766
                                                                             
Human   220 ----------------------------------------------------------------- 219

  Fly   767 SKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPR 831
                                                            ||:
Human   220 ------------------------------------------------PRD-------------- 222

  Fly   832 STATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEG 896
                ::||  |.:|||..||:.|.:..:..|||||.||||...|||:.....|.:|..|||:...
Human   223 ----IQAR--MRIHNNRVGRQVVTENLKRKCKCHGTSGSCQFKTCWRAAPEFRAVGAALRERLGR 281

  Fly   897 ATKVKINKRG------RLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSG 955
            |..:..:.|.      ||:.:.|      :.:|:|.::|||:|.....:..|||.||.|:|.|..
Human   282 AIFIDTHNRNSGAFQPRLRPRRL------SGELVYFEKSPDFCERDPTMGSPGTRGRACNKTSRL 340

  Fly   956 LESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLE-EHTCK 1004
            |:.|..||||||:|.......|||:|:|||||.|.|:.| ||.| .:.||
Human   341 LDGCGSLCCGRGHNVLRQTRVERCHCRFHWCCYVLCDEC-KVTEWVNVCK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	124/497 (25%)
WNT10B	NP_003385.2	Wnt_Wnt10b	45..389	CDD:381730	126/503 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..197		5/25 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152273
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740