Protein Alignment Wnt5 and WNT2

DIOPT Version :9

• Sequence 1: NP_001285407.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_003382.1
• Gene: WNT2 / 7472
• HGNCID: 12780
• Length: 360
• Species: Homo sapiens
• Alignment Length: 468
• Identity: 147/468 - (31%)
• Similarity: 210/468 - (44%)
• Gaps: 170/468 - (36%)

  Fly   548 CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTN-DETVFGPMTSLAA 611
            |.:..||.:||::.|.:|..||.|||:|......|||.||:..||||:|.: |.::||.:...::
Human    41 CDNVPGLVSSQRQLCHRHPDVMRAISQGVAEWTAECQHQFRQHRWNCNTLDRDHSLFGRVLLRSS 105

  Fly   612 PEMAFIHALAAATVTSFIARACRDGQLASCSCSRGSRPKQLHD--DWK----WGGCGDNLEFAYK 670
            .|.||::|:::|.|...|.|||..|::.||||.    ||::..  |.|    ||||.||:::..|
Human   106 RESAFVYAISSAGVVFAITRACSQGEVKSCSCD----PKKMGSAKDSKGIFDWGGCSDNIDYGIK 166

  Fly   671 FATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRK 735
            ||..|:|::|:
Human   167 FARAFVDAKER------------------------------------------------------ 177

  Fly   736 STEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKK 800
                                                                    ||
Human   178 --------------------------------------------------------KG------- 179

  Fly   801 KRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCH 865
                                   ||            ||:|||||||.|||:||.:..:..||||
Human   180 -----------------------KD------------ARALMNLHNNRAGRKAVKRFLKQECKCH 209

  Fly   866 GVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINKRGR-LQIKDLQFKVPTAHDLIYLDES 929
            ||||||:|.|||..::..|:.||||..||.||.:|.:|:.|. ..:.:.:||.||.:||:|.:.|
Human   210 GVSGSCTLRTCWLAMADFRKTGDYLWRKYNGAIQVVMNQDGTGFTVANERFKKPTKNDLVYFENS 274

  Fly   930 PDWC---RNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKC 991
            ||:|   |.:.:|   ||.||||:..|.|::||.::||||||:|.::....:|.|||||||.|:|
Human   275 PDYCIRDREAGSL---GTAGRVCNLTSRGMDSCEVMCCGRGYDTSHVTRMTKCGCKFHWCCAVRC 336

  Fly   992 EVCTKVLEEHTCK 1004
            :.|.:.|:.||||
Human   337 QDCLEALDVHTCK 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_001285407.1	wnt	554..1004	CDD:278536	143/460 (31%)
WNT2	NP_003382.1	wnt	43..349	CDD:306592	144/464 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152279
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3913
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326151at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X108
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750