Protein Alignment Wnt5 and Wnt10

DIOPT Version :10

• Sequence 1: NP_476924.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_609109.4
• Gene: Wnt10 / 34011
• FlyBaseID: FBgn0031903
• Length: 493
• Species: Drosophila melanogaster
• Alignment Length: 670
• Identity: 147/670 - (21%)
• Similarity: 207/670 - (30%)
• Gaps: 310/670 - (46%)

  Fly   436 SFKVSSEGSDGELLSRVERSQPSISSSSSSSSSSSRKIMPDYIKVSMENNTSVTDYFK-----HD 495
            :::.:|:|.:.:.|.:.::.|....|||||:|||              ||...|....     |.
  Fly    13 AWRATSKGHEQQQLPQQQKQQQEAGSSSSSNSSS--------------NNLVATPATSRHCNLHL 63

  Fly   496 VVMTSADVASDREFLIKNMEEHGGAGSANSHHNDTTPTADAYSETIDLNPNNCYSAIGLSNSQKK 560
            :||..  :|....:|      :|            .|...|          .|.|..||:..|.:
  Fly    64 IVMII--LACCTRWL------YG------------LPDGRA----------TCRSVPGLTKDQVE 98

  Fly   561 QCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAP---EMAFIHALAA 622
            .|.|.:.|..|...|...||:|||.||:..|||||:.:.::.....:||...   |.||..|::|
  Fly    99 LCYKASDVTAAALEGLDMAIRECQIQFQWHRWNCSSLSTKSRNPHASSLLKKGYRESAFAFAISA 163

  Fly   623 ATVTSFIARACRDGQLASCSCSRGSRPKQLHDD-------------------------------- 655
            |.|...:||||..|:|.||.|......|.|:.:
  Fly   164 AGVAHSVARACSQGRLMSCGCDPTINRKTLNKNLRQSLDKEKKQFLQYLETNQILTPEEEKKYER 228

  Fly   656 ------WKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGI 714
                  ||||||..|::|..:::..|:|.|||..:
  Fly   229 SKIASRWKWGGCSHNMDFGVEYSKLFLDCREKAGD------------------------------ 263

  Fly   715 KRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQE 779
                                                                          :|.
  Fly   264 --------------------------------------------------------------IQS 266

  Fly   780 KIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNL 844
            ||                                                             ||
  Fly   267 KI-------------------------------------------------------------NL 270

  Fly   845 HNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKYEGA-----------T 898
            |||.|||.||.......|||||:||||.|.|||:.......:|..|:.::..|           .
  Fly   271 HNNHAGRIAVSNNMEFRCKCHGMSGSCQLKTCWKSAPDFHIVGKVLKHQFRKAILVDQSNLGNGE 335

  Fly   899 KVKINKRGR----------------LQIKDLQ------------------------FKVPTAH-- 921
            .|.:.||.|                |...|..                        .:.|:|.
  Fly   336 PVVVLKRARNKKSNGGSGSGSTSPDLDSTDASGGHDDGGTGDSETRRHDELGVERGTRQPSADKN 400

  Fly   922 ----------DLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNIIVN 976
                      .|.|...||::|.........||.||.|::|::..:.|..||||||::  .:|..
  Fly   401 AARMARKLETSLFYYQRSPNFCERDLGADIQGTVGRKCNRNTTTSDGCTSLCCGRGHS--QVIQR 463

  Fly   977 --ERCNCKFHWCCQVKCEVC 994
              |||:|||.|||.|:||.|
  Fly   464 RAERCHCKFQWCCNVECEEC 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_476924.1	Wnt_Wnt5	548..1004	CDD:381711	124/553 (22%)
Wnt10	NP_609109.4	Wnt	83..493	CDD:393294	125/566 (22%)