Protein Alignment Wnt5 and wnt10b

DIOPT Version :10

• Sequence 1: NP_476924.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_835737.1
• Gene: wnt10b / 30308
• ZFINID: ZDB-GENE-980526-524
• Length: 427
• Species: Danio rerio
• Alignment Length: 552
• Identity: 131/552 - (23%)
• Similarity: 180/552 - (32%)
• Gaps: 256/552 - (46%)

  Fly   543 LNPNN-CYSAIGLSNSQKKQCVKHTSVMPAISRGARAAIQECQFQFKNRRWNCSTTNDETVFGPM 606
            |.||. |....||:..|.:.||:...|..:..:|.:.||.|||.|.:::|||||:..:.   |.:
Zfish    42 LTPNAVCLRLAGLTKKQMRLCVRSPDVTASALQGIQVAIHECQHQLRDQRWNCSSLENH---GKL 103

  Fly   607 TSLAA------PEMAFIHALAAATVTSFIARACRDGQLASCSCS--------------------- 644
            ...:|      .|.||..:|.||.|...:|.||..|:|..|.|.
Zfish   104 PHQSAILNRGFRESAFSLSLLAAGVVHSVASACSLGKLRGCGCEAKRRLDDDKIRLKLTQLQLQT 168

  Fly   645 ---------------------RGSRPKQLH-------------------DDWKWGGCGDNLEFAY 669
                                 .||.|..||                   |.|:||||..::.|..
Zfish   169 FQRSGVSLAGAGENTPELSSLHGSLPANLHSSHPMSLLKPLPDEVTMLQDTWEWGGCSHDIRFGV 233

  Fly   670 KFATDFIDSREKETNRETRGVKRKREEINKNRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVR 734
            :|:.|::|||
Zfish   234 RFSRDWLDSR------------------------------------------------------- 243

  Fly   735 KSTEAENSHILNENFDQHLLELEQRITKEILTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRK 799
                                                                             
Zfish   244 ----------------------------------------------------------------- 243

  Fly   800 KKRKNQRAAADAPAYPRNGIKESYKDGGILPRSTATVKARSLMNLHNNEAGRRAVIKKARITCKC 864
                         ..||:                  :.||:  .:|||..||:.|....|..|||
Zfish   244 -------------GSPRD------------------IHART--RIHNNRVGRQVVTDNMRRKCKC 275

  Fly   865 HGVSGSCSLITCWQQLSSIREIGDYLREKYEGATKVKINK---------------------RGRL 908
            ||.||||...|||......|.:|..||||:  .|.:.||.                     ||
Zfish   276 HGTSGSCQFKTCWYVSPEFRLVGSLLREKF--LTAIFINSQNKNNGVFNSRTGGSTGSDPLRG-- 336

  Fly   909 QIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKNSSGLESCAILCCGRGYNTKNI 973
                 |.:...:.:|:|.::|||:|....|:...||.||:|:|:|.|::.|..||||||:|....
Zfish   337 -----QRRRSISRELVYFEKSPDFCDREPAVDSLGTQGRICNKSSPGMDGCGSLCCGRGHNILKQ 396

  Fly   974 IVNERCNCKFHWCCQVKCEVCTKVLE-EHTCK 1004
            ..:|||:|:|||||.|.||.| ||.| .:.||
Zfish   397 ARSERCHCRFHWCCYVLCEEC-KVTEWVNVCK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt5	NP_476924.1	Wnt_Wnt5	548..1004	CDD:381711	126/544 (23%)
wnt10b	NP_835737.1	Wnt_Wnt10b	45..427	CDD:381730	127/547 (23%)