Protein Alignment Xrcc2 and XRCC2

DIOPT Version :10

• Sequence 1: NP_573302.1
• Gene: Xrcc2 / 32837
• FlyBaseID: FBgn0030931
• Length: 250
• Species: Drosophila melanogaster
• Sequence 2: NP_005422.1
• Gene: XRCC2 / 7516
• HGNCID: 12829
• Length: 280
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 39/159 - (24%)
• Similarity: 67/159 - (42%)
• Gaps: 16/159 - (10%)

  Fly    21 LVEISGPGNSGKSLVLQQLVAHCLVPYKFGGRQWSVLLINLSHKINRESLAKSIRMELKAYSVGE 85
            ::|..||..:||:.:|..|.|.|::|...||.:..||.|:..:..:...|...:...|...|
Human    43 ILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSS--- 104

  Fly    86 VIAAKCPTEEQLAEIAGECMSRVRFLNCFANDDVSTSLIDARYAIINDPGIQLVAMDTLSEFYWL 150
                        .||...|:.|...:.|.::..:..:|........:.|.:.|:.:|:||.|||:
Human   105 ------------EEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWI 157

  Fly   151 DEPKIAKRMSMYRH-YRLLQARLEKLCKD 178
            |.....:.:::... .|.....||||..|
Human   158 DRVNGGESVNLQESTLRKCSQCLEKLVND 186

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Xrcc2	NP_573302.1	P-loop containing Nucleoside Triphosphate Hydrolases	21..>178	CDD:476819	38/157 (24%)
XRCC2	NP_005422.1	XRCC2	41..243	CDD:410898	39/159 (25%)
		nucleotide binding domain A	48..55		3/6 (50%)
		nucleotide binding domain B	145..150		1/4 (25%)