Protein Alignment Pgant7 and GALNT14

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001240755.1
• Gene: GALNT14 / 79623
• HGNCID: 22946
• Length: 557
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 188/599 - (31%)
• Similarity: 282/599 - (47%)
• Gaps: 127/599 - (21%)

  Fly    13 RLALCLLVLLPLLYLLANWSDHHKRVQEAYHTRFGGPKFAHQRLE---GRPREVPKL------VD 68
            ||.|.:..:|.:..||..|                   ...::||   |...:.||:      |.
Human     7 RLVLPVFGVLWITVLLFFW-------------------VTKRKLEVPTGPEVQTPKVWSLFFKVA 52

  Fly    69 GLGNFEPKDVKPRSGPGENGEAHSLSPDKKHMSDA------SEMEYGMNIACSDEISMHRSVRDT 127
            |:..:.|:.....:.|.:.|..    |...|::..      .|.::.:      :..:...||.|
Human    53 GMSPWAPQVPVSPTPPYQRGHL----PTGGHLAVCHFPCLLQEAQFHL------QTQVFLQVRCT 107

  Fly   128 RLEECRHWDYPFDLPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQ 192
            .|..|.      |||.||:||.||||..|.|:||:.||::|:|||::.|||||||||:..:...|
Human   108 LLVYCT------DLPPTSIIITFHNEARSTLLRTIRSVLNRTPTHLIREIILVDDFSNDPDDCKQ 166

  Fly   193 LDEYVLQFKGLVKVIRNKEREGLIRTRSRGAMEATGEVIVFLDAHCEVNTNWLPPLLAPIYRDRT 257
            |.:.     ..||.:||.||:||:|:|.|||..|.|..:.|||:|||||.:||.|||..:..|.|
Human   167 LIKL-----PKVKCLRNNERQGLVRSRIRGADIAQGTTLTFLDSHCEVNRDWLQPLLHRVKEDYT 226

  Fly   258 VMTVPIIDGIDHKNFEYRPVYGTDNHFRGIFEWGMLYKENEVPRREQRRRAHNSEPYRSPTHAGG 322
            .:..|:||.|:...|.|   ..:.:..||.|:|.:.::..::...::.||...:||.|:|..|||
Human   227 RVVCPVIDIINLDTFTY---IESASELRGGFDWSLHFQWEQLSPEQKARRLDPTEPIRTPIIAGG 288

  Fly   323 LFAINREYFLELGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNF--GKL 385
            ||.|::.:|..||.||..:.:|||||||:||::|.||||:|.|||||||||:|...||.|  |..
Human   289 LFVIDKAWFDYLGKYDMDMDIWGGENFEISFRVWMCGGSLEIVPCSRVGHVFRKKHPYVFPDGNA 353

  Fly   386 ASKKKGPLITINYKRVIETWFDDTHKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDH 450
            .:..|      |.||..|.|.|: :|:|:|...|.|.....|::..:|.|:|.|.|:||:|::::
Human   354 NTYIK------NTKRTAEVWMDE-YKQYYYAARPFALERPFGNVESRLDLRKNLRCQSFKWYLEN 411

  Fly   451 IAYDVYDKFPGLPANLHWGELRSVASDGCLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGV 515
            |       :|.|          |:..:..:..                            |.:..
Human   412 I-------YPEL----------SIPKESSIQK----------------------------GNIRQ 431

  Fly   516 GERCVEADRQ------GIKLAVCRLGTVDGP------WQYNEHTKHLMHRVHKKCMALHPATQQL 568
            .::|:|:.||      .:||:.|  ..|.|.      |.:....:.|...:....:.|.|.. .:
Human   432 RQKCLESQRQNNQETPNLKLSPC--AKVKGEDAKSQVWAFTYTQQILQEELCLSVITLFPGA-PV 493

  Fly   569 SLGHCDVNDSYQQW 582
            .|..|...|..|||
Human   494 VLVLCKNGDDRQQW 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	135/308 (44%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	21/131 (16%)
GALNT14	NP_001240755.1	pp-GalNAc-T	119..413	CDD:133004	136/315 (43%)
		beta-trefoil_Ricin-like	418..557	CDD:483949	20/121 (17%)