Protein Alignment Pgant7 and Galnt1

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_077349.1
• Gene: Galnt1 / 79214
• RGDID: 620358
• Length: 559
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 223/594 - (37%)
• Similarity: 332/594 - (55%)
• Gaps: 53/594 - (8%)

  Fly     6 IRSGRICR--LALCLLVLLPLLYLLANWSDHHKRVQEAYHTRFGGPKFAHQRLEGRPR-EVPKLV 67
            :|....|:  ||..|:.:|..::||..:|:.:              |...::..|.|. :|.:||
  Rat     1 MRKFAYCKVVLATSLVWVLLDMFLLLYFSECN--------------KCEEKKERGLPAGDVLELV 51

  Fly    68 DGLGNFEPKDVKPRSGPGENGEAHSL-SPDKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLEE 131
            .          ||..||||.|:...: ..|::.|.:..::.. .|:..|:.|:.:||:.|.|||.
  Rat    52 Q----------KPHEGPGEMGKPVVIPKEDQEKMKEMFKINQ-FNLMASEMIAFNRSLPDVRLEG 105

  Fly   132 CRHWDYPFDLPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEY 196
            |:...||..||.|||:||||||.:|.|:|||||||:|||.||:.||:||||.|:::.|:..|:.|
  Rat   106 CKTKVYPDSLPTTSVVIVFHNEAWSTLLRTVHSVINRSPRHMIEEIVLVDDASERDFLKRPLESY 170

  Fly   197 VLQFKGLVKVIRNKEREGLIRTRSRGAMEATGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTV 261
            |.:.|..|.|||.::|.||||.|.:||..:.|:||.|||||||....||.||||.|..||..:..
  Rat   171 VKKLKVPVHVIRMEQRSGLIRARLKGAAVSKGQVITFLDAHCECTVGWLEPLLARIKHDRRTVVC 235

  Fly   262 PIIDGIDHKNFEYRPVYGTDNHFRGIFEWGMLYKENEVPRRE-QRRRAHNSEPYRSPTHAGGLFA 325
            ||||.|....|||  :.|:|..:.| |.|.:.::...||:|| .||:...:.|.|:||.|||||:
  Rat   236 PIIDVISDDTFEY--MAGSDMTYGG-FNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFS 297

  Fly   326 INREYFLELGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKKK 390
            |:|:||.|:|.||.|:.:|||||.|:||:||||||::|.|.||.||||:|...||.|    ....
  Rat   298 IDRDYFQEIGTYDAGMDIWGGENLEISFRIWQCGGTLEIVTCSHVGHVFRKATPYTF----PGGT 358

  Fly   391 GPLITINYKRVIETWFDDTHKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDV 455
            |.:|..|.:|:.|.|.|: .|.:||...|....:|.||||.::.|:.:|.||.|.|::::|
  Rat   359 GQIINKNNRRLAEVWMDE-FKNFFYIISPGVTKVDYGDISSRVGLRHKLQCKPFSWYLENI---- 418

  Fly   456 YDKFPGLPANLHW---GELRSVASDGCLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGE 517
               :|......|:   ||:|:|.::.|||:|..:....:|:..|||.|.||:....|..::...:
  Rat   419 ---YPDSQIPRHYFSLGEIRNVETNQCLDNMARKENEKVGIFNCHGMGGNQVFSYTANKEIRTDD 480

  Fly   518 RCVEADRQGIKLAVCRLGTVDGP--WQYNEHTKHLMHRVHKKCM--ALHPATQQLSLGHCDVNDS 578
            .|::..:....:.:.:...:.|.  |:|:.....|.|....:|:  |....:|..|:..|..:.|
  Rat   481 LCLDVSKLNGPVTMLKCHHLKGNQLWEYDPVKLTLQHVNSNQCLDKATEEDSQVPSIRDCTGSRS 545

  Fly   579 YQQWWFKEI 587
             |||..:.:
  Rat   546 -QQWLLRNV 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	150/307 (49%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	32/128 (25%)
Galnt1	NP_077349.1	Catalytic subdomain A	115..225		64/109 (59%)
		pp-GalNAc-T	119..419	CDD:133004	151/314 (48%)
		Catalytic subdomain B	285..347		40/61 (66%)
		beta-trefoil_Ricin_GALNT1	426..552	CDD:467344	32/126 (25%)