Protein Alignment Pgant7 and Galnt12

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001413928.1
• Gene: Galnt12 / 313233
• RGDID: 1562001
• Length: 576
• Species: Rattus norvegicus
• Alignment Length: 620
• Identity: 217/620 - (35%)
• Similarity: 308/620 - (49%)
• Gaps: 99/620 - (15%)

  Fly     6 IRSGRICRLALCLLVLLPLLYLLANWSDHHKRVQEAYHTRFGGPKFAHQRLEGRPREVPKLVDGL 70
            :|.||...|||..|..|                        |....|..| .|....||......
  Rat    14 LRRGREALLALLALAGL------------------------GAVLRARSR-SGTVDPVPTRTPHP 53

  Fly    71 GNFE---PKDVKPRSGPGENGEA--HSLSPDKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLE 130
            |..|   |:...|....|..|||  ..|..::..:.:.|...:.:||..||.||:||.:.:....
  Rat    54 GRHEPVLPRPPLPADALGAKGEAVRLQLQGEELRLQEESVQRHQINIYLSDRISLHRRLPERWNP 118

  Fly   131 ECRHWDYPFD-LPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLD 194
            .||...|.:| ||:|||:|.|:||.:|.|:|||:||::.||..:|.|:|||||:||:|:|:..|.
  Rat   119 LCREVKYDYDNLPKTSVVIAFYNEAWSTLLRTVYSVLETSPDILLEEVILVDDYSDREHLKEPLA 183

  Fly   195 EYVLQFKGLVKVIRNKEREGLIRTRSRGAMEATGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVM 259
            ..:.|.. .|::||..:||||:|.|..||..|.|||:.|||.|||.:..||.|||..|:...:.:
  Rat   184 NELSQLP-KVRLIRASKREGLVRARLLGASAARGEVLTFLDCHCECHEGWLEPLLQRIHEKESAV 247

  Fly   260 TVPIIDGIDHKNFEYRPVYGTDNHFRGIFEWGMLYKENEVPRREQRRRAHNSEPYRSPTHAGGLF 324
            ..|:||.||...|||....|...  .|.|:|.:::..:.||:||::......:..||||.|||||
  Rat   248 VCPVIDVIDWNTFEYLGNSGEPQ--IGGFDWRLVFTWHVVPQRERKLMRSPIDVIRSPTMAGGLF 310

  Fly   325 AINREYFLELGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKK 389
            |:::.||..||:||.|:.||||||.|.||:||||||::|..|||.||||:....||:..|..:
  Rat   311 AVSKRYFEYLGSYDTGMEVWGGENLEFSFRIWQCGGTLETHPCSHVGHVFPKQAPYSRSKALA-- 373

  Fly   390 KGPLITINYKRVIETWFDDTHKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYD 454
                   |..|..|.|.|| .||.:|.|.|.||....||::|:..|:.:|.||.|:||:|.:..:
  Rat   374 -------NSVRAAEVWMDD-FKELYYHRNPQARLEPFGDVTERKKLRAKLQCKDFKWFLDTVYPE 430

  Fly   455 VY--DKFPGLPANLHWGELRSVASDG-CLDSMGHQPPA---IMG----LTYCHGGGNNQLVRLNA 509
            ::  :..||.     :|.|.:....| |||   :.||:   :.|    |..|||.|.||.....:
  Rat   431 LHVPEDRPGF-----FGMLENRGLRGYCLD---YNPPSENNVEGHQVLLYLCHGMGQNQFFEYTS 487

  Fly   510 AGQLGVGER------CVEADRQGIKLAVCRLGTV----------DGPWQYNEHTKHLMHRVHKKC 558
            ..::....|      .||..:..:.:.:|: .||          ||.         |:|:...||
  Rat   488 RQEIRYNTRQPEACIAVEEGKDVLIMDLCK-DTVPENQEFVLQEDGT---------LVHKQSGKC 542

  Fly   559 MALHPATQQ-------LSLGHCDVNDSYQQWWFKE 586
            :   .||::       ..|..|..:|: |:|.|||
  Rat   543 V---EATEKEFDTSFAPHLRDCSSSDN-QRWLFKE 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	138/306 (45%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	36/152 (24%)
Galnt12	NP_001413928.1	None