Protein Alignment Pgant7 and gly-3

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_498722.1
• Gene: gly-3 / 176112
• WormBaseID: WBGene00001628
• Length: 612
• Species: Caenorhabditis elegans
• Alignment Length: 625
• Identity: 211/625 - (33%)
• Similarity: 332/625 - (53%)
• Gaps: 70/625 - (11%)

  Fly     5 TIRSGR--ICR--LALCLLVLLPLLYLLANWSDHHKRVQEAYHTRFGGPKFAHQRLEGRPREVPK 65
            ::..||  :||  :|..::.||..:.:|..:.|.....|:.:      |:  ..|:..|.|.:..
 Worm     3 SVGGGRSAVCRAVIATSIVWLLIDVVILFYYLDPSTSQQQPF------PE--DNRILNRARRIEP 59

  Fly    66 LVDGLGNFEPKDVKP----------------------------RSGPGENGEAH---SLSPDKKH 99
            |.....:....|..|                            ..|||.:|:..   ::..|||.
 Worm    60 LPPAAQHDSDPDAHPIQPEKQEKQVYPVDKETANQLRKLMETQAFGPGYHGQGGTGVTVPEDKKT 124

  Fly   100 MSDASEMEYGMNIACSDEISMHRSVRDTRLEECRHWDYPF---DLPRTSVIIVFHNEGFSVLMRT 161
            :.:...:|...|:..|:.||::|::.|.|.:.||......   .:|:||:|||||||.::.|:||
 Worm   125 IKEKRFLENQFNVVASEMISVNRTLPDYRSDACRTSGNNLKTAGMPKTSIIIVFHNEAWTTLLRT 189

  Fly   162 VHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEYVLQFKGLVKVIRNKEREGLIRTRSRGAMEA 226
            :||||:|||.|:|.|||||||.||::.|...||.|:..|...:.::..:.|.||||.|..|:..|
 Worm   190 LHSVINRSPRHLLEEIILVDDKSDRDYLVKPLDSYIKMFPIPIHLVHLENRSGLIRARLTGSEMA 254

  Fly   227 TGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFEYRPVYGTDNHFRGIFEWG 291
            .|::::|||||.||...||.||::.:..||..:..||||.|....|||  |..::..:.| |.|.
 Worm   255 KGKILLFLDAHVEVTDGWLEPLVSRVAEDRKRVVAPIIDVISDDTFEY--VTASETTWGG-FNWH 316

  Fly   292 MLYKENEVPRRE-QRRRAHNSEPYRSPTHAGGLFAINREYFLELGAYDPGLLVWGGENFELSFKI 355
            :.::...||:|| .||.:..|.|.::||.|||||||::::|.::|:||.|:.||||||.|:||::
 Worm   317 LNFRWYAVPKRELNRRGSDRSMPIQTPTIAGGLFAIDKQFFYDIGSYDEGMQVWGGENLEISFRV 381

  Fly   356 WQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKKKGPLITINYKRVIETWFDDTHKEYFYTREPL 420
            |.||||:|..||||||||:|...||.|....:|    :|..|..|..|.|.|: :|.:||...|.
 Worm   382 WMCGGSLEIHPCSRVGHVFRKQTPYTFPGGTAK----VIHHNAARTAEVWMDE-YKAFFYKMVPA 441

  Fly   421 ARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPGLPANLH-WGELRSVASDGCLDSMG 484
            ||.::.||:||:..|::.|.||||:|::::|    |.:.| |||:.. .|.:.:..::.|:|:.|
 Worm   442 ARNVEAGDVSERKKLRETLQCKSFKWYLENI----YPEAP-LPADFRSLGAIVNRFTEKCVDTNG 501

  Fly   485 HQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEADR-----QGIKLAVCRLG--TVDGPWQ 542
            .:.....|:..|||.|.||...|...|::...:.|:.:..     ..:||..|.:.  .|...:.
 Worm   502 KKDGQAPGIQACHGAGGNQAWSLTGKGEIRSDDLCLSSGHVYQIGSELKLERCSVSKINVKHVFV 566

  Fly   543 YNEHTKHLMHRVHKKCMALHPATQQLSLGHCDVNDSYQQW 582
            :::....|:|:...||:.  .|.|:::|..|.:....|.|
 Worm   567 FDDQAGTLLHKKTGKCVT--GADQRVTLDECGLGRKDQMW 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	141/307 (46%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	29/127 (23%)
gly-3	NP_498722.1	pp-GalNAc-T	173..473	CDD:133004	142/311 (46%)
		beta-trefoil_Ricin_GALNT1-like	481..608	CDD:467311	28/126 (22%)