Protein Alignment Pgant7 and GALNT13

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_001363332.1
• Gene: GALNT13 / 114805
• HGNCID: 23242
• Length: 571
• Species: Homo sapiens
• Alignment Length: 528
• Identity: 214/528 - (40%)
• Similarity: 308/528 - (58%)
• Gaps: 58/528 - (10%)

  Fly    81 RSGPGENGEAHSLSP--DKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLEECRHWDYPFDLPR 143
            :.||||.|:| .|.|  |::.|.:..::.. .|:..||.|:::||:.|.|||.|:...||.:||.
Human    54 QEGPGEMGKA-VLIPKDDQEKMKELFKINQ-FNLMASDLIALNRSLPDVRLEGCKTKVYPDELPN 116

  Fly   144 TSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEYVLQFKGLVKVIR 208
            |||:||||||.:|.|:|||:|||:|||.::|.|:|||||.|:::.|:..|:.||...:..||:||
Human   117 TSVVIVFHNEAWSTLLRTVYSVINRSPHYLLSEVILVDDASERDFLKLTLENYVKNLEVPVKIIR 181

  Fly   209 NKEREGLIRTRSRGAMEATGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFE 273
            .:||.||||.|.|||..:.|:||.|||||||....||.||||.|..||..:..||||.|....||
Human   182 MEERSGLIRARLRGAAASKGQVITFLDAHCECTLGWLEPLLARIKEDRKTVVCPIIDVISDDTFE 246

  Fly   274 YRPVYGTDNHFRGIFEWGMLYKENEVPRRE-QRRRAHNSEPYRSPTHAGGLFAINREYFLELGAY 337
            |  :.|:|..:.| |.|.:.::...||:|| .||:...:.|.|:||.|||||:|:|.||.|:|.|
Human   247 Y--MAGSDMTYGG-FNWKLNFRWYPVPQREMDRRKGDRTLPVRTPTMAGGLFSIDRNYFEEIGTY 308

  Fly   338 DPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKKKGPLITINYKRVI 402
            |.|:.:|||||.|:||:|||||||:|.|.||.||||:|...||.|    ....|.:|..|.:|:.
Human   309 DAGMDIWGGENLEMSFRIWQCGGSLEIVTCSHVGHVFRKATPYTF----PGGTGHVINKNNRRLA 369

  Fly   403 ETWFDDTHKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPGLPANLH 467
            |.|.|: .|::||...|....:|.||:|.:..|::.|.||.|.|::::|..|  .:.|....:|
Human   370 EVWMDE-FKDFFYIISPGVVKVDYGDVSVRKTLRENLKCKPFSWYLENIYPD--SQIPRRYYSL- 430

  Fly   468 WGELRSVASDGCLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEADRQGIKLAVC 532
             ||:|:|.::.|||:||.:....:|:..|||.|.||:....|..::...:.|::..|
Human   431 -GEIRNVETNQCLDNMGRKENEKVGIFNCHGMGGNQVFSYTADKEIRTDDLCLDVSR-------- 486

  Fly   533 RLGTVDGP--------------WQYNEHTKHLMHRVHKKCMAL--------HPATQQLSLGHCDV 575
                ::||              |:|:..|..|:|.:.:.|:::        ||..:.     |
Human   487 ----LNGPVIMLKCHHMRGNQLWEYDAETHTLLHIITQSCLSVNKVADGSQHPTVET-----C-- 540

  Fly   576 NDSYQQWW 583
            |||..|.|
Human   541 NDSTLQKW 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	149/307 (49%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	36/142 (25%)
GALNT13	NP_001363332.1	pp-GalNAc-T	118..418	CDD:133004	149/307 (49%)
		beta-trefoil_Ricin-like	425..552	CDD:483949	36/145 (25%)