Protein Alignment Pgant7 and GALNT5

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: XP_016858726.1
• Gene: GALNT5 / 11227
• HGNCID: 4127
• Length: 956
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 203/560 - (36%)
• Similarity: 284/560 - (50%)
• Gaps: 87/560 - (15%)

  Fly    75 PKDVKPRSGPGENGEAHSLSPDKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLEECRHWDYPF 139
            |:|.|   .||:.|....:...|:..::....|...|:..||.|.:.|::.|||...|.......
Human   432 PRDPK---APGQFGRPVVVPHGKEKEAERRWKEGNFNVYLSDLIPVDRAIEDTRPAGCAEQLVHN 493

  Fly   140 DLPRTSVIIVFHNEGFSVLMRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEYVLQFKGLV 204
            :||.||||:.|.:|.:|.|:|:|||||:|||.|::.||:||||||.|:.|:..||:|:.||. .|
Human   494 NLPTTSVIMCFVDEVWSTLLRSVHSVINRSPPHLIKEILLVDDFSTKDYLKDNLDKYMSQFP-KV 557

  Fly   205 KVIRNKEREGLIRTRSRGAMEATGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDH 269
            :::|.|||.||||.|..||..|||:|:.|||:|.|.|..||.|||..:|..|..:..|:|:.|:.
Human   558 RILRLKERHGLIRARLAGAQNATGDVLTFLDSHVECNVGWLEPLLERVYLSRKKVACPVIEVIND 622

  Fly   270 KNFEYRPVYGTDNHFRGIFEWGMLYKENEVPRRE-QRRRAHNSEPYRSPTHAGGLFAINREYFLE 333
            |:..|..|   ||..||||.|.|.:....:|... .:.|...::..|.|..|||||:|::.||.|
Human   623 KDMSYMTV---DNFQRGIFVWPMNFGWRTIPPDVIAKNRIKETDTIRCPVMAGGLFSIDKSYFFE 684

  Fly   334 LGAYDPGLLVWGGENFELSFKIWQCGGSIEWVPCSRVGHVYRGFMPYNFGKLASKKKGPLITINY 398
            ||.|||||.||||||.|||||:|.|||.||.:|||||||::|...||:|.|...|    .:..|.
Human   685 LGTYDPGLDVWGGENMELSFKVWMCGGEIEIIPCSRVGHIFRNDNPYSFPKDRMK----TVERNL 745

  Fly   399 KRVIETWFDDTHKEYFYTR--EPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPG 461
            .||.|.|.|: :||.||..  ..:.:.||:|::::|..|:|:|.||||:|:::::       ||.
Human   746 VRVAEVWLDE-YKELFYGHGDHLIDQGLDVGNLTQQRELRKKLKCKSFKWYLENV-------FPD 802

  Fly   462 LPANL--HWGELRSVASDGCLDSMGHQPPAIMGLTY----CHGGGNNQLVRLNAAGQLGVGERCV 520
            |.|.:  ..|.|.:||...|:        :|...|.    |.|....|.........:..||.|:
Human   803 LRAPIVRASGVLINVALGKCI--------SIENTTVILEDCDGSKELQQFNYTWLRLIKCGEWCI 859

  Fly   521 E--ADRQGIKLAVCRLGTVDGPWQYNEHTKHLMHRVHKKCMALH------------PATQQLSLG 571
            .  .|:..::|..|.        ..|:..|.|    ||.....|            ||...|.:.
Human   860 APIPDKGAVRLHPCD--------NRNKGLKWL----HKSTSVFHPELLSNSACGSFPALLSLQVN 912

  Fly   572 H-------------------------CDVNDSYQQWWFKE 586
            |                         ||....||:|.|::
Human   913 HIVFENNQQLLCLEGNFSQKILKVAACDPVKPYQKWKFEK 952

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	147/309 (48%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	33/166 (20%)
GALNT5	XP_016858726.1	pp-GalNAc-T	499..800	CDD:133004	147/316 (47%)
		beta-trefoil_Ricin_GALNT5	806..954	CDD:467314	32/167 (19%)