Protein Alignment Pgant7 and Galnt7

DIOPT Version :10

• Sequence 1: NP_573301.2
• Gene: Pgant7 / 32836
• FlyBaseID: FBgn0030930
• Length: 591
• Species: Drosophila melanogaster
• Sequence 2: NP_653332.3
• Gene: Galnt7 / 108150
• MGIID: 1349449
• Length: 657
• Species: Mus musculus
• Alignment Length: 570
• Identity: 257/570 - (45%)
• Similarity: 344/570 - (60%)
• Gaps: 32/570 - (5%)

  Fly    33 DHHKRVQEAYHTRFGGPKFAHQRLEGRPREVPKLVDG-LGNFEPKDVKPR---SGPGENGEAHSL 93
            |..:.|.:..:..|....|.::.        |.|..| |||||||:.:|.   .||||..:...|
Mouse   102 DSQRDVMQRQYLTFKPQTFTYRD--------PVLRPGVLGNFEPKEPEPHGVVGGPGEKAKPLVL 158

  Fly    94 SPDKKHMSDASEMEYGMNIACSDEISMHRSVRDTRLEECRHWDYPFDLPRTSVIIVFHNEGFSVL 158
            .|:.|....||..|:|.|:..||.||:.|||.|.|.|||::|.|..:|..:||:|||||||:|.|
Mouse   159 GPEYKQAVQASIKEFGFNMVASDMISLDRSVNDLRQEECKYWHYDENLLTSSVVIVFHNEGWSTL 223

  Fly   159 MRTVHSVIDRSPTHMLHEIILVDDFSDKENLRSQLDEYVLQFKGLVKVIRNKEREGLIRTRSRGA 223
            ||||||||.|:|...|.||:|:||||:||:|:.:||||:..:.|||||.||:.|||||:.||.||
Mouse   224 MRTVHSVIKRTPRKYLAEIVLIDDFSNKEHLKEKLDEYIKLWNGLVKVFRNERREGLIQARSIGA 288

  Fly   224 MEA-TGEVIVFLDAHCEVNTNWLPPLLAPIYRDRTVMTVPIIDGIDHKNFEYRPVYG--TDNHFR 285
            .:| .|:|:::|||||||..||..||:|||.:|||:.||||||.|....:|..|..|  .|.:.|
Mouse   289 QKAKLGQVLIYLDAHCEVAVNWYAPLVAPISKDRTICTVPIIDVISGNTYEIIPQGGGDEDGYAR 353

  Fly   286 GIFEWGMLYKENEVPRREQRRRAHNSEPYRSPTHAGGLFAINREYFLELGAYDPGLLVWGGENFE 350
            |.::|.||:|...:..||:|.|...:||||||..|||||||.:::|.|||.|||||.:|||||||
Mouse   354 GAWDWSMLWKRVPLTSREKRLRKTKTEPYRSPAMAGGLFAIEKDFFFELGLYDPGLQIWGGENFE 418

  Fly   351 LSFKIWQCGGSIEWVPCSRVGHVYR--GFM----PYNFGKLASKKKGPLITINYKRVIETWFDDT 409
            :|:|||||||.:.:||||||||:||  |:.    |...|...:.|       ||.||:|.|:|:
Mouse   419 ISYKIWQCGGKLLFVPCSRVGHIYRLEGWQGNPPPLYVGSSPTLK-------NYVRVVEVWWDE- 475

  Fly   410 HKEYFYTREPLARYLDMGDISEQLALKKRLNCKSFQWFMDHIAYDVYDKFPGLPANLHWGELRSV 474
            :|:|||...|.::.|..|||||....::..|||||:|||:.||||:...:|..|.|:.|||:|.:
Mouse   476 YKDYFYASRPESKALPYGDISELKKFREDHNCKSFKWFMEEIAYDITAHYPLPPRNVEWGEIRGL 540

  Fly   475 ASDGCLDSMGHQPPAIMGLTYCHGGGNNQLVRLNAAGQLGVGERCVEADRQGIKLAV--CRLGTV 537
            .:..|:||||......:.|..||..|.|||.|:|.|.||...::|:.....|.|:.:  |.|...
Mouse   541 ETAYCIDSMGKTNGGFVELGPCHRMGGNQLFRINEANQLMQYDQCLTKGPDGSKVMITHCNLNEF 605

  Fly   538 DGPWQYNEHTKHLMHRVHKKCMALHPATQQLSLGHCDVNDSYQQWWFKEI 587
            . .|||.:......|....||:.......|:.:..||.:...|:|....|
Mouse   606 K-EWQYFKSLHRFTHITSGKCLDRSEVLHQVFISTCDSSKMTQKWEMNNI 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pgant7	NP_573301.2	pp-GalNAc-T	145..452	CDD:133004	170/315 (54%)
		beta-trefoil_Ricin_GALNT7	464..586	CDD:467315	38/123 (31%)
Galnt7	NP_653332.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..66
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	83..105		1/2 (50%)
		Catalytic subdomain A	206..317		67/110 (61%)
		pp-GalNAc-T	210..518	CDD:133004	170/315 (54%)
		Catalytic subdomain B	381..443		44/61 (72%)
		beta-trefoil_Ricin_GALNT7	530..653	CDD:467315	38/123 (31%)